INT156465

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Plcb1) signal transduction (Plcb1) cell adhesion (Plcb1)
mRNA processing (Plcb1) nucleus (Plcb1) enzyme binding (Plcb1)
Anatomy Link Frequency
neurons 1
Plcb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 100.00 Very High Very High Very High
Thalamus 2 91.68 High High
Visceral pain 3 88.16 High High
Pain 6 75.00 Quite High
Kinase C 3 48.88 Quite Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

3 88.16 High High
Pain 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, although the firing modes of TC neurons are known to be affected by corticothalamic inputs via thalamic metabotropic glutamate receptor type 1 (mGluR1)-phospholipase C beta4 (PLCbeta4) pathway, its molecular mechanisms have not been well elucidated.
Regulation (affected) of PLCbeta4 in neurons associated with glutamate receptor
1) Confidence 0.10 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 19052225 Disease Relevance 0.07 Pain Relevance 0.35

General Comments

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