INT15654

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Context Info
Confidence 0.66
First Reported 1985
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 22
Total Number 23
Disease Relevance 12.20
Pain Relevance 2.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tg) extracellular region (Tg) Golgi apparatus (Tg)
endoplasmic reticulum (Tg)
Anatomy Link Frequency
thyroid 5
nails 2
smooth muscle 1
white blood cell 1
epithelium 1
Tg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 19 99.88 Very High Very High Very High
cINOD 1 99.84 Very High Very High Very High
Angina 1 97.72 Very High Very High Very High
imagery 2 95.28 Very High Very High Very High
rheumatoid arthritis 3 92.56 High High
Abeta 3 92.20 High High
Neuropathic pain 1 90.32 High High
substance P 1 89.52 High High
Somatostatin 2 88.96 High High
corticosteroid 2 87.68 High High
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 66 99.78 Very High Very High Very High
Thyroid Disease 7 99.72 Very High Very High Very High
INFLAMMATION 1 99.72 Very High Very High Very High
Cancer 51 99.32 Very High Very High Very High
Carcinoid 9 98.92 Very High Very High Very High
Metastasis 19 98.88 Very High Very High Very High
Thyroiditis 6 97.84 Very High Very High Very High
Angina 1 97.72 Very High Very High Very High
Hemorrhage 2 96.80 Very High Very High Very High
Pain 16 96.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[A case of metastatic rib tumor from thyroid cancer confirmed by the presence of thyroglobulin].
Gene_expression (presence) of thyroglobulin in thyroid associated with thyroid neoplasm and cancer
1) Confidence 0.66 Published 1991 Journal Nihon Kyobu Shikkan Gakkai Zasshi Section Title Doc Link 1753551 Disease Relevance 0.87 Pain Relevance 0.10
Anaplastic thyroid cancer (ATC) is a rare aggressive tumor arising from the follicular cells of the thyroid gland (as does well differentiated thyroid cancer, WDTC), but ATC cells do not retain any of the biological features of the original follicular cells, such as uptake of iodine and synthesis of thyroglobulin.
Gene_expression (synthesis) of thyroglobulin in thyroid associated with thyroid neoplasm and cancer
2) Confidence 0.61 Published 2008 Journal Minerva Endocrinol. Section Abstract Doc Link 18923370 Disease Relevance 1.00 Pain Relevance 0
High serum thyroglobulin levels.
Gene_expression (levels) of thyroglobulin
3) Confidence 0.60 Published 1987 Journal Cancer Section Title Doc Link 3440233 Disease Relevance 0.61 Pain Relevance 0.08
Serum thyroglobulin (Tg) levels were elevated in 92% of 38 patients with subacute "painful" thyroiditis in the early stage, independent of the extent of the disease and thyroid hormone concentrations.
Gene_expression (levels) of thyroglobulin in thyroid associated with pain, thyroiditis and disease
4) Confidence 0.59 Published 1985 Journal Arch. Intern. Med. Section Abstract Doc Link 3977482 Disease Relevance 0.33 Pain Relevance 0.22
Predictors of favourable outcome were shorter preoperative duration of TGN, older age at time of MVD, typical features, and vascular compression; moreover, complications, and previous neurodestructive procedures did not show significant effect on long-term pain relief.
Gene_expression (duration) of TGN
5) Confidence 0.58 Published 2010 Journal Br J Neurosurg Section Body Doc Link 20158348 Disease Relevance 0 Pain Relevance 0
Follow-up pelvic ultrasonography 1 year later showed no evidence of recurrent disease, and her serum thyroglobulin levels remained normal.


Gene_expression (levels) of thyroglobulin
6) Confidence 0.53 Published 2008 Journal Nature clinical practice. Endocrinology & metabolism Section Body Doc Link 18560398 Disease Relevance 0 Pain Relevance 0
[PET-FDG in thyroid cancer with high thyroglobulin levels and negative 131-I scan.
Gene_expression (levels) of thyroglobulin in thyroid associated with thyroid neoplasm
7) Confidence 0.53 Published 1999 Journal Rev Esp Med Nucl Section Title Doc Link 10074219 Disease Relevance 0.75 Pain Relevance 0.08
Serum thyroglobulin levels in the diagnosis and follow-up of subacute 'painful' thyroiditis.
Gene_expression (levels) of thyroglobulin associated with pain and thyroiditis
8) Confidence 0.52 Published 1985 Journal Arch. Intern. Med. Section Title Doc Link 3977482 Disease Relevance 0.49 Pain Relevance 0.39
Serum levels of TSH, thyroglobulin and thyroglobulin antibodies were measured.
Gene_expression (levels) of thyroglobulin
9) Confidence 0.47 Published 2008 Journal Nature clinical practice. Endocrinology & metabolism Section Body Doc Link 18560398 Disease Relevance 0 Pain Relevance 0
The patient had no symptoms of hyperthyroidism, and her thyroid function and serum thyroglobulin levels were normal.
Gene_expression (levels) of thyroglobulin in thyroid associated with thyroid disease
10) Confidence 0.47 Published 2008 Journal Nature clinical practice. Endocrinology & metabolism Section Abstract Doc Link 18560398 Disease Relevance 0.53 Pain Relevance 0.09
The levels of thyroglobulin were shown increased, being the 131I scan negative.
Gene_expression (levels) of thyroglobulin
11) Confidence 0.47 Published 1999 Journal Rev Esp Med Nucl Section Abstract Doc Link 10074219 Disease Relevance 0.78 Pain Relevance 0.10
Serum levels of TSH, thyroglobulin and thyroglobulin antibodies were measured.
Gene_expression (levels) of thyroglobulin
12) Confidence 0.47 Published 2008 Journal Nature clinical practice. Endocrinology & metabolism Section Body Doc Link 18560398 Disease Relevance 0 Pain Relevance 0
We observed a massive increase of thyroglobulin (Tg) concentrations in cases of DTC that started 36-48 h after SETA and did not occur in cases of ATC.
Gene_expression (concentrations) of thyroglobulin associated with thyroid neoplasm
13) Confidence 0.16 Published 2007 Journal Endocr. Relat. Cancer Section Abstract Doc Link 17914113 Disease Relevance 1.31 Pain Relevance 0.28
Laboratory tests showed hyperthyroidism and elevated levels of thyroglobulin and C-reactive protein.
Gene_expression (levels) of thyroglobulin associated with thyroid disease
14) Confidence 0.11 Published 2002 Journal Pediatr Hematol Oncol Section Abstract Doc Link 12051591 Disease Relevance 1.33 Pain Relevance 0.10
Thyroglobulin was strongly positive in the follicular lining epithelium and weakly positive in the carcinoid cells adjacent to the follicular area.
Gene_expression (positive) of Thyroglobulin in epithelium associated with carcinoid
15) Confidence 0.10 Published 1986 Journal Int. J. Gynecol. Pathol. Section Abstract Doc Link 3759324 Disease Relevance 0.77 Pain Relevance 0.15
The tumor was composed of interlacing fascicles of spindle-shaped cells that expressed smooth muscle actin and vimentin but were negative for cytokeratins and thyroglobulin.
Neg (negative) Gene_expression (negative) of thyroglobulin in smooth muscle associated with cancer
16) Confidence 0.09 Published 2008 Journal Ann Diagn Pathol Section Abstract Doc Link 18164417 Disease Relevance 0.76 Pain Relevance 0.14
The finding of concurrent production of calcitonin and thyroglobulin within the same tumor is enough to question the dogma of the separate origin of follicular cells and C-cells.
Gene_expression (production) of thyroglobulin associated with cancer
17) Confidence 0.08 Published 1985 Journal Ultrastruct Pathol Section Abstract Doc Link 3901454 Disease Relevance 0.62 Pain Relevance 0.26
Serum thyroglobulin levels were monitored as indicators of thyroid manipulation, and C-reactive protein and white blood cell count were monitored to assess surgical stress response.
Gene_expression (levels) of thyroglobulin in white blood cell
18) Confidence 0.08 Published 2005 Journal Head Neck Section Body Doc Link 15459914 Disease Relevance 0 Pain Relevance 0
The groups with and without TSAb were comparable with regard to sex, age, anti-inflammatory drugs, serum thyroglobulin levels, antithyroglobulin and antimicrosomal antibodies, rheumatoid factor, as well as to the serum levels of thyroxine and 3, 5, 3'-triiodothyronine.
Gene_expression (levels) of thyroglobulin associated with inflammation and cinod
19) Confidence 0.05 Published 1987 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2892878 Disease Relevance 0.36 Pain Relevance 0.23
Tumor cells showed diffuse immunopositivity for calcitonin, HMB-45, carcinoembryonic antigen, synaptophysin, chromogranin, vimentin and epithelial membrane antigen but focal paranuclear dot-like positivity for cytokeratin (Fig 2a–f), and were negative for thyroglobulin, S-100, melan-A and TTF (Table 2).
Neg (negative) Gene_expression (negative) of thyroglobulin associated with cancer
20) Confidence 0.04 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2253502 Disease Relevance 0.67 Pain Relevance 0

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