INT156558

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (BACE2) peptidase activity (BACE2) Golgi apparatus (BACE2)
endoplasmic reticulum (BACE2) plasma membrane (TRPV6) transmembrane transport (TRPV6)
TRPV6 (Homo sapiens)
BACE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Abeta 8 95.88 Very High Very High Very High
tetrodotoxin 3 90.20 High High
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 3 99.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mechanistic studies measuring C-terminal fragments of amyloid precursor protein (APP) suggested that catL elevated alpha-secretase activity, thereby suppressing Abeta42 levels.
catL Negative_regulation (suppressing) of alpha-secretase associated with alzheimer's dementia
1) Confidence 0.00 Published 2009 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 19064719 Disease Relevance 0.23 Pain Relevance 0.58

General Comments

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