INT156606

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.88
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome (Acd) nucleus (Acd) intracellular (Acd)
DNA binding (Acd)
Acd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bioavailability 1 99.96 Very High Very High Very High
Dopamine 9 98.40 Very High Very High Very High
Inflammation 6 94.72 High High
Morphine 1 90.92 High High
Ventral tegmentum 1 78.44 Quite High
Nucleus accumbens 1 72.64 Quite High
psoriasis 2 69.52 Quite High
pruritus 2 68.68 Quite High
Neurobehavioral 1 58.24 Quite High
antagonist 12 55.08 Quite High
Disease Link Frequency Relevance Heat
Conjunctival Diseases 32 100.00 Very High Very High Very High
Hypersensitivity 36 99.56 Very High Very High Very High
Conjunctivitis 80 96.00 Very High Very High Very High
INFLAMMATION 6 94.72 High High
Alcohol Addiction 1 93.36 High High
Sneezing 6 93.28 High High
Rhinitis 16 91.08 High High
Conjunctiva Disease 46 90.88 High High
Erythema 2 70.44 Quite High
Psoriasis 2 69.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that modulation of ACD bioavailability may influence the addictive profile of EtOH by decreasing its psychotropic effects and possibly leading the way to new pharmacological treatments of alcoholism.
Positive_regulation (modulation) of ACD associated with alcohol addiction and bioavailability
1) Confidence 0.42 Published 2009 Journal Drug Alcohol Depend Section Abstract Doc Link 19070441 Disease Relevance 0.09 Pain Relevance 0.61
In addition, the recent increase in severity of ACD is raising concerns.
Positive_regulation (increase) of ACD associated with conjunctival diseases
2) Confidence 0.11 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2694001 Disease Relevance 2.61 Pain Relevance 0.05
ACD are mainly caused by type I allergic reactions.
Positive_regulation (caused) of ACD associated with hypersensitivity and conjunctival diseases
3) Confidence 0.10 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2694001 Disease Relevance 1.17 Pain Relevance 0.10

General Comments

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