INT15662

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 1991
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Drd2) plasma membrane (Drd2) signal transducer activity (Drd2)
Anatomy Link Frequency
neurons 2
striatum 2
caudate-putamen 2
Drd2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 14 100.00 Very High Very High Very High
Enkephalin 3 99.66 Very High Very High Very High
Ventral tegmentum 1 93.20 High High
Substantia nigra 1 92.12 High High
dopamine receptor 2 91.72 High High
Glutamate 2 77.64 Quite High
projection neuron 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Disease 2 5.00 Very Low Very Low Very Low
Movement Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A smaller but consistent increase in dopamine D2 receptor mRNA levels was also found on adjacent sections of the striatum only in animals injected with 150 micrograms of 6-hydroxydopamine.
Positive_regulation (increase) of Transcription (levels) of dopamine D2 receptor in striatum associated with dopamine
1) Confidence 0.39 Published 1993 Journal Brain Res. Section Abstract Doc Link 7902185 Disease Relevance 0 Pain Relevance 0.40
Macroscopic analysis demonstrated that haloperidol treatment two times 1 mg/kg per day during seven, 14 and 21 days increased D2 receptor mRNA level in the caudate-putamen.
Positive_regulation (increased) of Transcription (level) of D2 receptor in caudate-putamen
2) Confidence 0.25 Published 1991 Journal Neuroscience Section Abstract Doc Link 1754061 Disease Relevance 0 Pain Relevance 0.08
Striatal neurons express increased level of dopamine D2 receptor mRNA in response to haloperidol treatment: a quantitative in situ hybridization study.
Positive_regulation (increased) of Transcription (express) of D2 receptor in neurons associated with dopamine and enkephalin
3) Confidence 0.22 Published 1991 Journal Neuroscience Section Title Doc Link 1754061 Disease Relevance 0 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox