INT156622

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.33
Pain Relevance 2.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Creb1) mitochondrion (Creb1) Golgi apparatus (Umod)
DNA binding (Creb1) extracellular space (Umod) extracellular region (Umod)
Anatomy Link Frequency
nucleus accumbens 3
hippocampus 1
Umod (Rattus norvegicus)
Creb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Oxycodone 18 100.00 Very High Very High Very High
psychological dependence 2 100.00 Very High Very High Very High
Nucleus accumbens 6 99.52 Very High Very High Very High
Hippocampus 6 98.64 Very High Very High Very High
addiction 2 85.84 High High
Physical dependence 2 66.28 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 4 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All these results suggest that l-THP can inhibit oxycodone-induced psychological dependence by affecting phosphorylation of CREB and ERK in nucleus accumbens and hippocampus of rats.
l-THP Regulation (affecting) of Phosphorylation (phosphorylation) of CREB in nucleus accumbens associated with nucleus accumbens, oxycodone, hippocampus and psychological dependence
1) Confidence 0.05 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19071107 Disease Relevance 0.17 Pain Relevance 1.14
All these results suggest that l-THP can inhibit oxycodone-induced psychological dependence by affecting phosphorylation of CREB and ERK in nucleus accumbens and hippocampus of rats.
l-THP Regulation (affecting) of in hippocampus Phosphorylation (phosphorylation) of CREB in nucleus accumbens associated with nucleus accumbens, oxycodone, hippocampus and psychological dependence
2) Confidence 0.02 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19071107 Disease Relevance 0.17 Pain Relevance 1.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox