INT156631

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Scn10a) transmembrane transport (Scn10a)
Anatomy Link Frequency
DRG 2
Scn10a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 4 99.26 Very High Very High Very High
intrathecal 1 80.00 Quite High
sodium channel 2 75.00 Quite High
Kinase C 2 75.00 Quite High
Inflammation 2 25.00 Low Low
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 5 99.86 Very High Very High Very High
INFLAMMATION 4 99.08 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data show that, after a period of recurring inflammatory stimuli, an intense and prolonged nociceptive response is elicited by a minimum inflammatory stimulus and that this pro-nociceptive state depends on Na(V)1.8 mRNA up-regulation in the DRG.
Regulation (depends) of Positive_regulation (up-regulation) of Na(V)1.8 in DRG associated with nociception and inflammatory stimuli
1) Confidence 0.26 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 19073148 Disease Relevance 0.61 Pain Relevance 0.34

General Comments

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