INT156685

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Context Info
Confidence 0.22
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 9
Disease Relevance 1.94
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASAP1) cytoplasm (ASAP1)
Anatomy Link Frequency
lung 2
PSCs 1
bladder 1
ASAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 1 100.00 Very High Very High Very High
Chronic pancreatitis 2 98.36 Very High Very High Very High
cva 30 97.88 Very High Very High Very High
lidocaine 2 71.40 Quite High
anesthesia 8 60.48 Quite High
interstitial cystitis 4 50.00 Quite Low
adenocard 2 20.24 Low Low
Catecholamine 9 5.00 Very Low Very Low Very Low
Dopamine 8 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Embolism 30 98.28 Very High Very High Very High
Pancreatitis 6 93.72 High High
Fibrosis 1 91.28 High High
Hypertension 33 89.52 High High
Cystitis 1 81.24 Quite High
Right Ventricular Dysfunction 4 80.00 Quite High
Tricuspid Valve Insufficiency 43 70.24 Quite High
Peripheral Arterial Disease 32 63.44 Quite High
Acid Reflux 10 57.20 Quite High
Pulmonary Hypertension 112 55.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SULT4A1 is one of the hSULTs that is most divergent in sequence, and examination of the binding pocket revealed two significant differences that are predicted to affect PAP binding.
Regulation (affect) of PAP
1) Confidence 0.22 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0 Pain Relevance 0
This may also be the explanation for the minimal effect of the serotonin receptor blocker ketanserin on PAP and cardiac output in patients with acute pulmonary embolism [28].
Regulation (effect) of PAP associated with pulmonary embolism, cva and serotonin
2) Confidence 0.21 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2859373 Disease Relevance 0.61 Pain Relevance 0.25
Assuming a protective role of PAP, we investigated its effects on human PSCs.
Regulation (role) of PAP in PSCs
3) Confidence 0.20 Published 2009 Journal Pancreatology Section Abstract Doc Link 19077460 Disease Relevance 0.35 Pain Relevance 0.19
HIP/PAP immunoreactivity was observed in the urothelium of 88.2% of patients with IC (15/17) and in 5.9% of bladder tissues of controls (1/17).
Regulation (immunoreactivity) of PAP in bladder
4) Confidence 0.20 Published 2010 Journal Urology Section Body Doc Link 19646740 Disease Relevance 0.08 Pain Relevance 0
Systolic PAP values were employed to determine mean PAP using the following experimental formula: Mean PAP (in mmHg) = 0.61*systolic PAP + 2 [24].
Regulation (values) of PAP
5) Confidence 0.15 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868165 Disease Relevance 0.41 Pain Relevance 0.13
Systolic PAP values were employed to determine mean PAP using the following experimental formula: Mean PAP (in mmHg) = 0.61*systolic PAP + 2 [24].
Regulation (values) of PAP
6) Confidence 0.13 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868165 Disease Relevance 0.39 Pain Relevance 0.13
Hb-induced changes in PAP and lung compliance (Figs 1 and 2), while only modest changes in the other variables were observed (Fig 2,Table 1).
Regulation (changes) of PAP in lung
7) Confidence 0.11 Published 1997 Journal Crit Care Section Body Doc Link PMC28996 Disease Relevance 0 Pain Relevance 0
However, were clearly demonstrated the potential for inhaled NO to modulate the increased PAP and decreased lung compliance without major effects in the systemic circulation.
Regulation (modulate) of PAP in lung
8) Confidence 0.08 Published 1997 Journal Crit Care Section Body Doc Link PMC28996 Disease Relevance 0.09 Pain Relevance 0
Perioperative administration of BiPAP, excellent pain control by continuous epidural infusion of local anesthetic, and the avoidance of endotracheal intubation may have contributed to this patient's uncomplicated postoperative course.


Regulation (control) of BiPAP
9) Confidence 0.06 Published 2009 Journal Reg Anesth Pain Med Section Body Doc Link 19258991 Disease Relevance 0 Pain Relevance 0

General Comments

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