INT156717

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl1) extracellular region (Cxcl1)
Cxcl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 1 100.00 Very High Very High Very High
Hyperalgesia 8 98.90 Very High Very High Very High
antagonist 3 97.64 Very High Very High Very High
nociceptor 3 90.40 High High
intrathecal 1 86.24 High High
Inflammation 4 79.88 Quite High
cytokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Hyperalgesia 8 98.90 Very High Very High Very High
INFLAMMATION 3 79.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-administration of the selective P2X3,2/3 receptors antagonist A-317491, or the non-selective P2X3 receptor antagonist, TNP-ATP, with carrageenan blocked the mechanical hyperalgesia induced by carrageenan, and significantly reduced the increased concentration of tumor necrosis factor alpha (TNF-alpha) and chemokine-induced chemoattractant-1 (CINC-1) but not of interleukin-1 beta (IL-1 beta) induced by carrageenan.
Neg (not) Positive_regulation (induced) of Neg (not) Positive_regulation (increased) of CINC-1 associated with chemokine, necrosis, hyperalgesia, cancer and antagonist
1) Confidence 0.18 Published 2009 Journal Pain Section Abstract Doc Link 19081189 Disease Relevance 0.97 Pain Relevance 0.98

General Comments

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