INT156750

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Gpt, Gpt) cytoplasm (Gpt, Gpt) cellular_component (Gpt)
biological_process (Gpt)
Gpt (Rattus norvegicus)
Gpt (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 1 99.46 Very High Very High Very High
Disease Link Frequency Relevance Heat
Obesity 1 77.32 Quite High
Hepatotoxicity 3 75.00 Quite High
Infection 1 47.76 Quite Low
Hepatitis 1 47.28 Quite Low
Cirrhosis 1 46.72 Quite Low
Liver Disease 1 45.76 Quite Low
Injury 2 40.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conclusion: Using animal models of hepatoxicity induced by carbon tetrachloride and acetaminophen, we found that both serum ALT1 and ALT2 protein levels were significantly elevated and correlated with ALT activity, providing, for the first time, the molecular basis for the elevated total serum ALT activity.
ALT1 Positive_regulation (elevated) of ALT associated with paracetamol
1) Confidence 0.27 Published 2009 Journal Hepatology Section Abstract Doc Link 19085960 Disease Relevance 0.22 Pain Relevance 0.10

General Comments

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