INT156776

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.74
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc22a12) transmembrane transporter activity (Slc22a12) plasma membrane (Slc22a12)
transmembrane transport (Slc22a12)
Anatomy Link Frequency
blood 2
Slc22a12 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 2 87.04 High High
headache 2 77.80 Quite High
Pain 2 76.32 Quite High
Glutamate 1 24.64 Low Low
Neurotransmitter 1 22.96 Low Low
cINOD 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urolithiasis 2 85.92 High High
Myoglobinuria 2 85.28 High High
Vomiting 2 78.28 Quite High
Headache 2 77.80 Quite High
Oliguria 2 77.40 Quite High
Pain 2 76.32 Quite High
Acute Renal Failure 10 75.00 Quite High
Inborn Genetic Diseases 2 67.16 Quite High
Targeted Disruption 1 63.52 Quite High
Cancer 42 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Polymerase chain reaction of a urate anion exchanger known to regulate blood urate level (SLC22A12 gene: URAT1) demonstrated that homozygous mutations in exon 4 (W258X).
Regulation (regulate) of SLC22A12 in blood
1) Confidence 0.25 Published 2008 Journal Am. J. Med. Sci. Section Abstract Doc Link 19092327 Disease Relevance 0.84 Pain Relevance 0.20
Polymerase chain reaction of a urate anion exchanger known to regulate blood urate level (SLC22A12 gene: URAT1) demonstrated that homozygous mutations in exon 4 (W258X).
Regulation (regulate) of URAT1 in blood
2) Confidence 0.25 Published 2008 Journal Am. J. Med. Sci. Section Abstract Doc Link 19092327 Disease Relevance 0.84 Pain Relevance 0.20
Even though there is no change in the expression levels of URAT1 and many other transporters in c/ebp??
Neg (no) Regulation (change) of URAT1
3) Confidence 0.10 Published 2008 Journal AAPS J Section Body Doc Link PMC2751467 Disease Relevance 0.06 Pain Relevance 0

General Comments

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