INT156836

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ETS1, MAPK7) cell differentiation (MAPK7) nucleoplasm (MAPK7)
DNA binding (ETS1) cytoplasm (MAPK7) cytosol (MAPK7)
Anatomy Link Frequency
Caco-2 2
ETS1 (Homo sapiens)
MAPK7 (Homo sapiens)
Pain Link Frequency Relevance Heat
member 8 1 98.68 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERK5-mediated phosphorylation of the transcription factor Ets-1 enhanced 1,25(OH)(2)D(3)-mediated CYP24 gene transcription in proliferating but not differentiated Caco-2 cells due to reduced levels of ERK5 and Ets-1 (total and phosphoprotein levels) in differentiated cells.
Ets-1 Positive_regulation (enhanced) of Phosphorylation (phosphorylation) of ERK5 in Caco-2
1) Confidence 0.14 Published 2009 Journal J. Cell. Physiol. Section Abstract Doc Link 19097033 Disease Relevance 0 Pain Relevance 0.10

General Comments

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