INT15692

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Context Info
Confidence 0.27
First Reported 1991
Last Reported 2005
Negated 2
Speculated 4
Reported most in Abstract
Documents 4
Total Number 8
Disease Relevance 4.75
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
uterus 1
oviduct 1
placentas 1
ovary 1
HTC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
methadone 6 100.00 Very High Very High Very High
Opioid 1 99.84 Very High Very High Very High
MU agonist 1 98.40 Very High Very High Very High
opioid receptor 4 98.08 Very High Very High Very High
Enkephalin 6 96.88 Very High Very High Very High
abdominal pain 1 88.60 High High
methotrexate 4 71.28 Quite High
Pain 3 53.68 Quite High
Dismenorea 2 50.00 Quite Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chordoma 131 100.00 Very High Very High Very High
Cancer 72 100.00 Very High Very High Very High
Ectopic Pregnancy 4 99.52 Very High Very High Very High
Endodermal Sinus Tumor 3 99.52 Very High Very High Very High
Syndrome 3 99.16 Very High Very High Very High
Precocious Puberty 1 93.12 High High
Genetic Predisposition To Disease 4 92.84 High High
Reprotox - General 1 2 92.20 High High
Dysgerminoma 2 91.20 High High
Abdominal Pain 1 88.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genetic changes might be indeed extremely rare in adenomyosis, or CGH was not sensitive enough to detect candidate genes.


Neg (not) Regulation (sensitive) of CGH
1) Confidence 0.27 Published 2002 Journal Anal. Quant. Cytol. Histol. Section Body Doc Link 11865944 Disease Relevance 0.08 Pain Relevance 0
In the meantime, early detection of ectopic pregnancy became possible due to sensitive serum hCG and progesterone combined assays with transvaginal sonography and a knowledge of risk factors.
Spec (possible) Regulation (sensitive) of hCG associated with ectopic pregnancy
2) Confidence 0.18 Published 1997 Journal Ann Chir Section Abstract Doc Link 9297859 Disease Relevance 0.48 Pain Relevance 0.09
In vitro release of acetylcholine and hCG from trophoblast tissue of methadone-exposed placentas was not modulated by opioids.
Neg (not) Regulation (modulated) of hCG in placentas associated with methadone and opioid
3) Confidence 0.15 Published 1993 Journal Membr Biochem Section Abstract Doc Link 8395641 Disease Relevance 0 Pain Relevance 0.91
Genetic alterations in chordoma: cytogenetics, FISH and CGH
Regulation (alterations) of CGH associated with chordoma
4) Confidence 0.09 Published 2005 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2837065 Disease Relevance 1.72 Pain Relevance 0
Diagnosis depends mainly on age, abdominal symptoms, size and consistency of the tumor, and tumor markers AFP and hCG.
Regulation (depends) of hCG associated with cancer
5) Confidence 0.00 Published 1995 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 7661594 Disease Relevance 2.22 Pain Relevance 0.09
The objectives of the experiments reported here were to (a) examine the presence of immunoreactive methionine-enkephalin (ir-MENK) in rabbit ovary, oviduct, and uterus and in a rabbit endometrial cell line (HRE-H9), (b) characterize ir-MENK biochemically, (c) investigate the effect of eCG + hCG treatment on the synthesis and secretion of ir-MENK in vivo, and (d) study the effect of K+ depolarization on the secretion of ir-MENK from HRE-H9 cells.
Spec (investigate) Regulation (effect) of hCG in ovary associated with enkephalin
6) Confidence 0.00 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 1756206 Disease Relevance 0.09 Pain Relevance 0.17
The objectives of the experiments reported here were to (a) examine the presence of immunoreactive methionine-enkephalin (ir-MENK) in rabbit ovary, oviduct, and uterus and in a rabbit endometrial cell line (HRE-H9), (b) characterize ir-MENK biochemically, (c) investigate the effect of eCG + hCG treatment on the synthesis and secretion of ir-MENK in vivo, and (d) study the effect of K+ depolarization on the secretion of ir-MENK from HRE-H9 cells.
Spec (investigate) Regulation (effect) of hCG in oviduct associated with enkephalin
7) Confidence 0.00 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 1756206 Disease Relevance 0.09 Pain Relevance 0.17
The objectives of the experiments reported here were to (a) examine the presence of immunoreactive methionine-enkephalin (ir-MENK) in rabbit ovary, oviduct, and uterus and in a rabbit endometrial cell line (HRE-H9), (b) characterize ir-MENK biochemically, (c) investigate the effect of eCG + hCG treatment on the synthesis and secretion of ir-MENK in vivo, and (d) study the effect of K+ depolarization on the secretion of ir-MENK from HRE-H9 cells.
Spec (investigate) Regulation (effect) of hCG in uterus associated with enkephalin
8) Confidence 0.00 Published 1991 Journal Biol. Reprod. Section Abstract Doc Link 1756206 Disease Relevance 0.09 Pain Relevance 0.17

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