INT156966

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.13
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc17a5) cytoplasmic membrane-bounded vesicle (Slc17a5) plasma membrane (Slc17a5)
transmembrane transport (Slc17a5) lysosome (Slc17a5)
Slc17a5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 98.12 Very High Very High Very High
Paracetamol 9 97.16 Very High Very High Very High
ischemia 10 62.88 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 1 99.00 Very High Very High Very High
Pneumonia 1 98.12 Very High Very High Very High
Toxicity 2 96.44 Very High Very High Very High
Necrosis 1 94.72 High High
Overdose 1 78.84 Quite High
Sprains And Strains 1 74.60 Quite High
Hepatotoxicity 2 73.36 Quite High
Injury 5 73.20 Quite High
Cv Unclassified Under Development 9 62.88 Quite High
Reperfusion Injury 2 62.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a significant inhibition (p<0.05) in the elevation of AST and ALT was observed in mice that received UBG and GIBG compared with APAP-treated mice.
Negative_regulation (inhibition) of Localization (elevation) of AST associated with paracetamol
1) Confidence 0.34 Published 2009 Journal Chem. Biol. Interact. Section Abstract Doc Link 19109935 Disease Relevance 0.69 Pain Relevance 0.77
AST release was reduced significantly more by treatment with
SNO-HSA-OA5 than with SNO-HSA-OA3 120 min after reperfusion
(Fig. 1A). 
Negative_regulation (reduced) of Localization (release) of AST
2) Confidence 0.02 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2596408 Disease Relevance 0.44 Pain Relevance 0.09

General Comments

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