INT156976

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 5.25
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TNFAIP3) peptidase activity (TNFAIP3) nucleus (TNFAIP3)
DNA binding (TNFAIP3) ligase activity (TNFAIP3) cytoplasm (TNFAIP3)
TNFAIP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 29 100.00 Very High Very High Very High
Crohn's disease 3 79.68 Quite High
spinal inflammation 3 78.68 Quite High
Multiple sclerosis 3 77.52 Quite High
Migraine 1 62.56 Quite High
fibrosis 1 50.12 Quite High
visual analogue scale 1 28.96 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Sicca syndrome 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 29 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 9 100.00 Very High Very High Very High
Autoimmune Disease 11 99.10 Very High Very High Very High
Diabetes Mellitus 15 99.08 Very High Very High Very High
Disease 24 79.68 Quite High
Low Back Pain 3 78.68 Quite High
Demyelinating Disease 3 77.52 Quite High
Infection 2 76.00 Quite High
Fever 1 65.52 Quite High
Chills 1 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings extend our knowledge of susceptibility locus sharing across different autoimmune diseases, and provide convincing evidence that the RA/SLE locus 6q23/TNFAIP3 is a newly identified T1D locus.
Gene_expression (/) of TNFAIP3 associated with autoimmune disease, diabetes mellitus, rheumatoid arthritis and systemic lupus erythematosus
1) Confidence 0.65 Published 2009 Journal Genes Immun. Section Abstract Doc Link 19110536 Disease Relevance 1.54 Pain Relevance 0.28
These findings extend our knowledge of susceptibility locus sharing across different autoimmune diseases, and provide convincing evidence that the RA/SLE locus 6q23/TNFAIP3 is a newly identified T1D locus.
Gene_expression (locus) of TNFAIP3 associated with autoimmune disease, diabetes mellitus, rheumatoid arthritis and systemic lupus erythematosus
2) Confidence 0.65 Published 2009 Journal Genes Immun. Section Abstract Doc Link 19110536 Disease Relevance 1.54 Pain Relevance 0.28
These findings extend our knowledge of susceptibility locus sharing across different autoimmune diseases, and provide convincing evidence that the RA/SLE locus 6q23/TNFAIP3 is a newly identified T1D locus.
Gene_expression (/) of TNFAIP3 associated with autoimmune disease, diabetes mellitus, rheumatoid arthritis and systemic lupus erythematosus
3) Confidence 0.65 Published 2009 Journal Genes Immun. Section Abstract Doc Link 19110536 Disease Relevance 1.55 Pain Relevance 0.28
The DAS28, HAQ 20, CRP, and ESR differences between week 0 (start point) and weeks 8, 16, and 24, were compared for the RF (–) and RF (+) patients, and anti-CCP (–) and anti-CCP (+) patients.
Gene_expression (compared) of HAQ 20
4) Confidence 0.01 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727907 Disease Relevance 0.62 Pain Relevance 0.09

General Comments

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