INT157080

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl) extracellular region (Ghrl) plasma membrane (Gnrhr)
signal transducer activity (Gnrhr) cytoplasm (Ghrl)
Ghrl (Rattus norvegicus)
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 23 86.72 High High
medulla 1 70.24 Quite High
tetrodotoxin 1 51.84 Quite High
nud 7 51.40 Quite High
Action potential 1 48.72 Quite Low
antagonist 2 42.40 Quite Low
Morphine 10 24.60 Low Low
opiate 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
qutenza 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 1 99.60 Very High Very High Very High
Gastric Motility Disorder 8 93.76 High High
Diabetes Mellitus 13 85.08 High High
Neuropathic Pain 1 71.12 Quite High
Dyspepsia 7 51.40 Quite High
Burns 9 37.92 Quite Low
Ileus 17 35.80 Quite Low
Disease 14 5.00 Very Low Very Low Very Low
Colitis 5 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ghrelin is a potent stimulant for growth hormone (GH) secretion and feeding.
Ghrelin Positive_regulation (stimulant) of Localization (secretion) of growth hormone
1) Confidence 0.23 Published 2009 Journal Peptides Section Abstract Doc Link 19118591 Disease Relevance 0 Pain Relevance 0.09
Being the ligand of growth hormone secretagogue receptor, ghrelin has been shown to induce growth hormone secretion [53] and insulin resistance [54]; such effects would cause serious unfavorable side effects in particular subsets of patients.
ghrelin Positive_regulation (induce) of Localization (secretion) of growth hormone associated with insulin resistance
2) Confidence 0.01 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2915793 Disease Relevance 0.70 Pain Relevance 0.17

General Comments

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