INT157186

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.54
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cps1) protein complex (Cps1) ligase activity (Cps1)
cytoplasm (Cps1)
Anatomy Link Frequency
brain 1
Cps1 (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 35 100.00 Very High Very High Very High
qutenza 8 100.00 Very High Very High Very High
GABAergic 17 68.12 Quite High
depression 2 56.00 Quite High
sSRI 3 55.00 Quite High
fluoxetine 1 54.32 Quite High
antidepressant 1 50.84 Quite High
spastic colon 5 50.00 Quite Low
Serotonin 1 45.56 Quite Low
Glutamate 2 27.52 Quite Low
Disease Link Frequency Relevance Heat
Stroke 1 84.52 Quite High
Appetite Loss 1 63.28 Quite High
Amblyopia 5 61.76 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

2 59.32 Quite High
Panic Disorder 1 57.96 Quite High
Obsessive-compulsive Disorder 1 57.24 Quite High
Depression 2 56.00 Quite High
Retts Disease 5 51.68 Quite High
Functional Bowel Disorder 3 50.00 Quite Low
Syndrome 6 49.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After 12 weeks of treatment, subjects with abuse history showed significantly higher CPS (t = 2.422, P = 0.018) than subjects without a history and less mean change of CPS (t = 3.506, P = 0.001).
Regulation (change) of CPS
1) Confidence 0.22 Published 2009 Journal J Clin Pharm Ther Section Body Doc Link 19125906 Disease Relevance 0 Pain Relevance 0
The participation of capsaicin (Cps)-sensitive afferent fibers in this phenomenon was evaluated.
Regulation (participation) of Cps associated with qutenza
2) Confidence 0.11 Published 2009 Journal Braz. J. Med. Biol. Res. Section Abstract Doc Link 19855904 Disease Relevance 0 Pain Relevance 0.37
There is increasing consensus on the concept that not only does brain inhibition control the closure of CPs and adult cortical plasticity, but that it may also be linked to the pathogenesis of developmental intellectual disabilities (see Fernandez and Garner, 2007 for a recent review).
Regulation (control) of CPs in brain
3) Confidence 0.03 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2854574 Disease Relevance 0.48 Pain Relevance 0.17
As has been mentioned in the previous section, the coordinated regulation of CS on CPS (the first enzyme of the ornithine cycle, converts ammonia, originating from amino acid degradation, into urea) or arginase (the last enzyme of the cycle) via CEBP-?
Regulation (regulation) of CPS associated with corticosteroid
4) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.13

General Comments

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