INT157210

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Context Info
Confidence 0.21
First Reported 2002
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 7
Disease Relevance 1.19
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CSH1) extracellular region (CSH1)
Anatomy Link Frequency
muscle 4
fibroblasts 2
Median nerve 2
mononuclear cells 2
CSH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 10 83.96 Quite High
Inflammatory marker 2 75.00 Quite High
Glutamate receptor 2 47.84 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cockayne Syndrome 55 92.20 High High
Osteogenic Sarcomas 2 90.80 High High
Contact Dermatitis 28 89.40 High High
Fibrosarcoma 1 87.92 High High
Aging 4 81.84 Quite High
Hypersensitivity 11 78.20 Quite High
INFLAMMATION 14 75.00 Quite High
Hypoxia 2 72.40 Quite High
Contagious Ecthyma 6 66.44 Quite High
Neurodegenerative Disease 1 52.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immortalized CSB (CS1AN) fibroblasts expressing either wild-type CSB cDNA (CSB-wt line) or enhanced green fluorescent protein (CSB-null line) were generated as described [25].
Positive_regulation (generated) of Gene_expression (expressing) of CS1AN in fibroblasts
1) Confidence 0.21 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2268245 Disease Relevance 0.52 Pain Relevance 0
Immediately after the onset of exercise, independent simulation of activity-dependent kL predicted that an elevation in [V]pl preceded the larger but slower elevation in [sR1]pl (Fig. 9B).
Positive_regulation (elevation) of Gene_expression (preceded) of pl
2) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.06 Pain Relevance 0
50% elevation in [sR1]pl (peaking ?
Positive_regulation (elevation) of Gene_expression (peaking) of pl
3) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.07 Pain Relevance 0
Men and women showed significant and nearly identical decreases in total muscle CSA after 14 D of immobilization (men?
Positive_regulation (muscle) of Gene_expression (total) of CSA in muscle
4) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716517 Disease Relevance 0 Pain Relevance 0
Men and women showed significant and nearly identical decreases in total muscle CSA after 14 D of immobilization (men?
Positive_regulation (after) of Gene_expression (total) of CSA in muscle
5) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716517 Disease Relevance 0 Pain Relevance 0
At positive antigen stimulated sites there was an early expression of CS-1 fibronectin (2 hours), followed by CCL17 and a later accumulation of alplha4/beta1+ (CD49d), CD3+, CD68+, CXCR3+ and CCR5+ mononuclear cells.
Positive_regulation (stimulated) of Gene_expression (expression) of CS-1 in mononuclear cells
6) Confidence 0.04 Published 2002 Journal BMC Dermatol Section Abstract Doc Link PMC122084 Disease Relevance 0.53 Pain Relevance 0.12
Median nerve CSA, ADC, and FA were analyzed at standardized anatomic levels.
Spec (analyzed) Positive_regulation (Median nerve) of Spec (analyzed) Gene_expression (analyzed) of CSA in Median nerve
7) Confidence 0.03 Published 2009 Journal Skeletal Radiol. Section Body Doc Link 19132371 Disease Relevance 0 Pain Relevance 0

General Comments

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