INT157287

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cfl1) cytoskeleton (Cfl1) nucleus (Cfl1)
intracellular (Cfl1) cytoskeleton organization (Cfl1) cytoplasm (Cfl1)
Anatomy Link Frequency
neuronal 2
Cfl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 2 83.40 Quite High
Lasting pain 1 72.44 Quite High
Disease Link Frequency Relevance Heat
Injury 2 92.12 High High
Frailty 2 83.68 Quite High
Pain 1 72.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show that transplantation of pre-differentiated ES cells activate both brain-derived neurotrophic factor (BDNF) and interleukin-6 (IL-6) signaling pathways in the host tissue, leading to activation of cAMP/PKA, phosporylation of cofilin and synapsin I, and promoting regenerative growth and neuronal survival.
Positive_regulation (activation) of Phosphorylation (phosporylation) of cofilin in neuronal
1) Confidence 0.11 Published 2009 Journal J. Neurotrauma Section Abstract Doc Link 19138107 Disease Relevance 0.41 Pain Relevance 0.15

General Comments

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