INT15734

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Context Info
Confidence 0.18
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Xcl1) extracellular region (Xcl1) cell-cell signaling (Xcl1)
Anatomy Link Frequency
neurons 1
Xcl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 83.20 Quite High
Neuropeptide 3 35.92 Quite Low
addiction 3 5.00 Very Low Very Low Very Low
drug abuse 2 5.00 Very Low Very Low Very Low
Endocannabinoid 2 5.00 Very Low Very Low Very Low
narcan 1 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Cannabinoid receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 15 5.00 Very Low Very Low Very Low
Weight Gain 8 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 5 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Hyperphagia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, this data indicate that the sensitivity toward positive hedonic aspects of rewarding stimuli is transiently enhanced while for negatively valued stimuli it is attenuated in adolescent rats and these findings are consistent with our present observation of enhanced SCM intake during puberty.
Negative_regulation (observation) of SCM
1) Confidence 0.18 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0
Comparisons of the density values (corresponding to mRNA levels), from these slice explants, found that: (1) cellular LHRH mRNA levels decreased in the absence of serum, whereas cellular OT mRNA levels did not significantly change under these conditions; (2) the presence of TTX in the media resulted in an overall decrease in cellular LHRH mRNA values in both SCM and SFM, and (3) the OT neurons in these slice cultures appear to be composed of a heterogeneous population, with one cell subtype responding to TTX with an increase in cellular OT mRNA levels.
Negative_regulation (decrease) of SCM in neurons
2) Confidence 0.02 Published 1991 Journal Neuroendocrinology Section Abstract Doc Link 1758575 Disease Relevance 0 Pain Relevance 0.16

General Comments

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