INT157382

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Context Info
Confidence 0.58
First Reported 2007
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 17
Total Number 17
Disease Relevance 3.93
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
facial muscles 1
plasma 1
Csi (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 48 100.00 Very High Very High Very High
anesthesia 99 96.36 Very High Very High Very High
Versed 5 95.60 Very High Very High Very High
Ultiva 8 95.04 Very High Very High Very High
Hippocampus 8 57.36 Quite High
Central nervous system 5 5.80 Low Low
Pain 33 5.00 Very Low Very Low Very Low
positron emission tomography 16 5.00 Very Low Very Low Very Low
vincristine 10 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 371 100.00 Very High Very High Very High
Dyspnea 1 97.56 Very High Very High Very High
Pressure And Volume Under Development 2 96.72 Very High Very High Very High
Targeted Disruption 16 91.72 High High
Coma 15 91.56 High High
Disease 48 88.28 High High
Recurrence 23 87.64 High High
Cancer 39 86.68 High High
Brain Injury 4 86.04 High High
Hypothermia 3 82.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A negative correlation was found between CSI and BS.
Gene_expression (found) of CSI
1) Confidence 0.58 Published 2009 Journal Paediatr Anaesth Section Body Doc Link 19143957 Disease Relevance 0 Pain Relevance 0
Twenty four hours later, the CSI was appeared with fluctuations that correlated to muscular twitching in the facial muscles.
Gene_expression (appeared) of CSI in facial muscles
2) Confidence 0.58 Published 2008 Journal Cases J Section Body Doc Link PMC2561013 Disease Relevance 0.69 Pain Relevance 0.21
In the past, most centers have treated adult patients in analogy to pediatric multidisciplinary treatment protocols including extensive neurosurgical resection, CSI and chemotherapy.
Gene_expression (resection) of CSI
3) Confidence 0.48 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2939548 Disease Relevance 0.53 Pain Relevance 0
CONCLUSIONS: The absolute values of the BIS and CSI were not significantly different during propofol-fentanyl-nitrous oxide anesthesia.
Gene_expression (values) of CSI
4) Confidence 0.33 Published 2010 Journal J Anesth Section Body Doc Link 20339885 Disease Relevance 0 Pain Relevance 0
These maps were then overlaid on the central slices of the IR-FSE scan, which were virtually aligned with the CSI data.
Gene_expression (aligned) of CSI associated with imagery
5) Confidence 0.22 Published 2008 Journal Journal of Neurology, Neurosurgery, and Psychiatry Section Body Doc Link PMC2582338 Disease Relevance 0 Pain Relevance 0.15
The objective of this study was to analyse the correlation between ocular reflexes, CSI and estimated propofol plasma concentrations (PropCP) in dogs during induction of anaesthesia with propofol.
Gene_expression (reflexes) of CSI in plasma
6) Confidence 0.13 Published 2009 Journal Res. Vet. Sci. Section Abstract Doc Link 19339028 Disease Relevance 0 Pain Relevance 0
The CSI monitoring was not consistent with the clinical observations observed in the different stages of depth anaesthesia.
Gene_expression (monitoring) of CSI
7) Confidence 0.13 Published 2009 Journal Res. Vet. Sci. Section Abstract Doc Link 19339028 Disease Relevance 0 Pain Relevance 0
b) Number of missed CSI, such as clinically important CSI not identified during initial ED visit;
Gene_expression (missed) of CSI associated with injury
8) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.30 Pain Relevance 0
Number of missed CSI, such as number of clinically important CSI not identified during initial ED visit.
Gene_expression (missed) of CSI associated with injury
9) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.37 Pain Relevance 0
b) Number of missed CSI, such as clinically important CSI not identified during initial ED visit;
Neg (not) Gene_expression (identified) of CSI associated with injury
10) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.29 Pain Relevance 0
b) Number of missed CSI, such as clinically important CSI not identified during initial ED visit;
Gene_expression (important) of CSI associated with injury
11) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.29 Pain Relevance 0
Number of missed CSI, such as number of clinically important CSI not identified during initial ED visit.
Gene_expression (missed) of CSI associated with injury
12) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.37 Pain Relevance 0
b) Number of missed CSI, such as clinically important CSI not identified during initial ED visit;
Gene_expression (missed) of CSI associated with injury
13) Confidence 0.10 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.30 Pain Relevance 0
According to the RNAi mechanism-based rules [31], [32], two siRNAs (Hsi1 and Hsi2) targeting the different sites of HongrES1 gene and a non-silencing siRNA (Csi) as scrambled control were designed and synthesized.
Gene_expression (synthesized) of Csi
14) Confidence 0.10 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2606034 Disease Relevance 0.22 Pain Relevance 0
The "criterion interpretation" of the rule, such as positive or negative for CSI, will be made by the investigators based on the status of the patient for the component variables as documented by the physician.
Neg (negative) Gene_expression (negative) of CSI associated with injury
15) Confidence 0.09 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.19 Pain Relevance 0
Two siRNAs (Hsi1 and Hsi2) targeting HongrES1 sequence and non-silencing siRNA (Csi) for scrambled control were synthesized by Shanghai GeneChem Inc (Shanghai, China).
Gene_expression (synthesized) of Csi
16) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2606034 Disease Relevance 0.07 Pain Relevance 0.06
The CSI tended to stabilize in values of 40-60 at intermediate levels of hypnosis, whereas BIS stabilized in values of 20-40 at deeper anesthetic levels [12].
Gene_expression (stabilize) of CSI
17) Confidence 0.07 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2946031 Disease Relevance 0.29 Pain Relevance 0.40

General Comments

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