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Context Info
Confidence 0.68
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.97
Pain Relevance 1.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CX3CR1) plasma membrane (CX3CR1) signal transducer activity (CX3CR1)
Anatomy Link Frequency
kidney 1
CX3CR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 9 98.32 Very High Very High Very High
Pain 6 92.00 High High
chemokine 15 90.80 High High
Neuritis 5 90.40 High High
Inflammation 43 83.36 Quite High
Angina 1 80.04 Quite High
fibrosis 4 79.04 Quite High
glial activation 1 60.20 Quite High
Neuropathic pain 1 59.20 Quite High
antagonist 1 56.64 Quite High
Disease Link Frequency Relevance Heat
Diabetic Nephropathy 5 99.24 Very High Very High Very High
Pancreatitis 9 98.32 Very High Very High Very High
Pain 5 92.00 High High
Neuritis 5 90.40 High High
Adhesions 12 89.48 High High
Fibrosis 6 88.24 High High
INFLAMMATION 42 83.36 Quite High
Hypertrophy 1 81.16 Quite High
Cv General 3 Under Development 1 80.04 Quite High
Coronary Artery Disease 45 70.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, the protein levels of both CX3CR1 and fractalkine were upregulated.
Positive_regulation (upregulated) of CX3CR1
1) Confidence 0.68 Published 2009 Journal Lab. Invest. Section Abstract Doc Link 19153557 Disease Relevance 2.03 Pain Relevance 1.70
Upregulated fractalkine and CX3CR1 levels were present in the early stage of diabetic kidney disease in rats.28 The aforementioned data suggest that fractalkine and CX3CR1 have an important role in the progression of diabetic nephropathy, functioning as an arrest chemokine in monocyte/macrophage adhesion before migration into the kidney.
Positive_regulation (Upregulated) of CX3CR1 in kidney associated with chemokine, adhesions and diabetic nephropathy
2) Confidence 0.17 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2762434 Disease Relevance 0.88 Pain Relevance 0.21

General Comments

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