INT157492

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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.69
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Foxp3) intracellular (Foxp3) embryo development (Foxp3)
DNA binding (Foxp3) cytoplasm (Foxp3)
Anatomy Link Frequency
effector T cells 1
T cell 1
Foxp3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 46 87.12 High High
Neuritis 4 86.88 High High
Inflammatory response 4 85.60 High High
Inflammation 51 84.64 Quite High
rheumatoid arthritis 50 84.56 Quite High
chemokine 24 72.24 Quite High
Osteoarthritis 1 47.92 Quite Low
agonist 10 5.00 Very Low Very Low Very Low
complementary and alternative medicine 10 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 3 98.44 Very High Very High Very High
Optic Neuritis 4 87.36 High High
INFLAMMATION 54 85.24 High High
Rheumatoid Arthritis 50 84.56 Quite High
Disease 23 81.52 Quite High
Multiple Sclerosis 4 75.00 Quite High
Eosinophilia 3 67.52 Quite High
Asthma 104 64.48 Quite High
Contact Dermatitis 2 60.44 Quite High
Chronic Disease 1 59.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, Foxp3 mRNA expression was remarkably increased in LNCs from PCl and KP-treated mice.
Transcription (expression) of Foxp3
1) Confidence 0.61 Published 2009 Journal J. Dermatol. Sci. Section Body Doc Link 19157794 Disease Relevance 0.06 Pain Relevance 0
Foxp3 mRNA transcription was down-regulated at 11-19 days post-immunization.
Transcription (transcription) of Foxp3 mRNA associated with immunization
2) Confidence 0.61 Published 2010 Journal Int. J. Mol. Med. Section Abstract Doc Link 20428790 Disease Relevance 0.80 Pain Relevance 0.39
Regulatory T cells express the transcription factor Foxp3 and control effector T cells through cell contacts and the release of transforming growth factor-?
Transcription (transcription) of Foxp3 in effector T cells
3) Confidence 0.32 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582809 Disease Relevance 0.47 Pain Relevance 0.28
Outcome measures included T cell proliferation and IL-4, IL-5, and IL-13 secretion (assessed by [3H]-thymidine incorporation and ELISA, respectively) and characterization of the induced Treg by qRT-PCR for FoxP3, LAG3, CTLA4, and IL-10 mRNA expression.
Transcription (expression) of FoxP3 in T cell
4) Confidence 0.11 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 0.36 Pain Relevance 0.14

General Comments

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