INT15752

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Context Info
Confidence 0.40
First Reported 1991
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 15
Total Number 15
Disease Relevance 14.57
Pain Relevance 2.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
smooth muscle 1
muscle 1
vagus nerves 1
Ema (Mus musculus)
Pain Link Frequency Relevance Heat
nud 27 99.04 Very High Very High Very High
fibrosis 1 97.92 Very High Very High Very High
Pain 15 92.72 High High
abdominal pain 8 91.64 High High
c fibre 5 88.48 High High
imagery 7 86.92 High High
qutenza 2 83.92 Quite High
Snapping jaw 1 83.56 Quite High
Angina 1 83.56 Quite High
Central nervous system 1 82.12 Quite High
Disease Link Frequency Relevance Heat
Cancer 83 99.86 Very High Very High Very High
Synovial Sarcoma 12 99.80 Very High Very High Very High
Carcinoma 2 99.76 Very High Very High Very High
Meningioma 10 99.70 Very High Very High Very High
Pneumothorax 3 99.14 Very High Very High Very High
Dyspepsia 27 99.04 Very High Very High Very High
Rhinitis 9 98.40 Very High Very High Very High
Fibrosis 1 97.92 Very High Very High Very High
Leiomyosarcoma 4 97.80 Very High Very High Very High
Ulcers 2 97.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cooling the vagus nerves to 7 degrees C, during the pneumothorax, produced a slight though not significant increase in EMA.
Neg (not) Positive_regulation (increase) of EMA in vagus nerves associated with pneumothorax
1) Confidence 0.40 Published 1991 Journal J. Appl. Physiol. Section Abstract Doc Link 1761476 Disease Relevance 0.27 Pain Relevance 0.45
Therefore, in the present brief review, we would like to introduce EMA and its usefulness, especially physical activity data as an object variable in EMA.
Positive_regulation (introduce) of EMA
2) Confidence 0.38 Published 2008 Journal Biopsychosoc Med Section Body Doc Link PMC2475521 Disease Relevance 0.65 Pain Relevance 0.14
Immunohistochemical studies revealed the tumor to be positive for epithelial membrane antigen (EMA) and muscle actin but negative for desmin, and S-100.
Positive_regulation (positive) of EMA in muscle associated with cancer
3) Confidence 0.37 Published 2000 Journal Hinyokika Kiyo Section Abstract Doc Link 10806578 Disease Relevance 0.88 Pain Relevance 0.08
Immunohistochemically, the epithelial component was cytokeratin positive and focally reactive for EMA.
Positive_regulation (reactive) of EMA
4) Confidence 0.30 Published 2009 Journal Int. J. Surg. Pathol. Section Abstract Doc Link 18397900 Disease Relevance 0.75 Pain Relevance 0.13
Immunohistochemical studies confirmed the diagnosis of meningioma with positive reactions for epithelial membrane antigen (EMA) and vimentin (all tested).
Positive_regulation (reactions) of EMA associated with meningioma
5) Confidence 0.27 Published 2000 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 10800982 Disease Relevance 1.72 Pain Relevance 0.10
All three groups were screened for IgA antiendomysium antibody (EMA) and IgA antitissue transglutaminase antibody (tTG), which were detected by the ELISA test (BMD, Marne la Vallee, France).
Positive_regulation (screened) of EMA
6) Confidence 0.17 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995907 Disease Relevance 1.38 Pain Relevance 0.60
Synovial sarcoma are also positive for EMA, vimentin, BCL-2, CD99 and calponin.
Positive_regulation (positive) of EMA associated with synovial sarcoma
7) Confidence 0.16 Published 2006 Journal Cytojournal Section Body Doc Link PMC1562442 Disease Relevance 0.76 Pain Relevance 0
Immunohistochemical analysis showed that the tumor was strongly and diffusely positive for cytokeratins with high and low molecular weight, and focally positive for vimentin and epithelial membrane antigen (EMA), but it was negative for carcinoembryonic antigen, Factor VIII, alpha-fetoprotein and Leu-M1.
Positive_regulation (positive) of EMA associated with cancer
8) Confidence 0.12 Published 2001 Journal Pathol. Int. Section Abstract Doc Link 11881736 Disease Relevance 1.57 Pain Relevance 0.12
Immunohistochemical studies were positive for CD99, S-100, and CD45 and negative for desmin, actin, chromogranin, epithelial membrane antigen (EMA), and cytokeratin.
Positive_regulation (negative) of EMA
9) Confidence 0.11 Published 2007 Journal Quintessence Int Section Abstract Doc Link 17432791 Disease Relevance 1.01 Pain Relevance 0.16
On immunohistochemistry, the tumor cells were strongly positive for vimentin, moderately positive for actin along the periphery of the cytoplasm, and negative for cytokeratin, EMA, myoglobin, S-100, CEA, Factor XIIIa, HMB-45, and HAM56 and KP-1.
Positive_regulation (negative) of EMA associated with cancer
10) Confidence 0.11 Published 1996 Journal Ultrastruct Pathol Section Abstract Doc Link 8789215 Disease Relevance 1.04 Pain Relevance 0.06
Immunohistochemical studies showed focal positivity for cytokeratin 7, CK 5/6, synaptophysin, and carcinoembryonic antigen (CEA), diffuse positive staining for epithelial membrane antigen (EMA) and BerEP4; and negative staining for cytokeratin 20, TTF-1, and GFAP.
Positive_regulation (staining) of EMA
11) Confidence 0.09 Published 2009 Journal Neuropathology Section Abstract Doc Link 18715273 Disease Relevance 0.20 Pain Relevance 0.05
Seventy five percent of patients were found to have positive anti-gliadin antibodies (AGA) at diagnosis and 68% had positive endomysial antibodies (EMA) while 91% patients were positive for EMA, AGA or both (95% confidence interval 79.3–102.7%). 90% had positive anti-tTG (95% CI 71.4–108.5%).
Positive_regulation (positive) of EMA
12) Confidence 0.07 Published 2006 Journal Nutr J Section Body Doc Link PMC1574337 Disease Relevance 2.02 Pain Relevance 0.20
Immunohistochemically, the tumor cells showed strong diffuse positivity for HMB-45 while they were negative for c-kit, smooth muscle actin, cytokeratin, S-100, vimentin, desmin, chromogranin, synaptophysin, EMA, and CD-34.
Positive_regulation (negative) of EMA in smooth muscle associated with cancer
13) Confidence 0.07 Published 2007 Journal Tumori Section Abstract Doc Link 17455882 Disease Relevance 0.56 Pain Relevance 0.13
By immunohistochemistry, the carcinoma cells were positive for cytokeratin AE1/AE3, cytokeratin 5/6, EMA, and MIC-2 (membranous staining).
Positive_regulation (positive) of EMA associated with carcinoma
14) Confidence 0.05 Published 2006 Journal Pediatr. Dev. Pathol. Section Abstract Doc Link 16944983 Disease Relevance 0.60 Pain Relevance 0.12
Histologically, the tumor cells are polygonal with abundant eosinophilic cytoplasm and eccentric nuclei and on immunostaining, these cells are variably positive for desmin, vimentin, GFAP, CK, EMA, SMA and synaptophysin [17].
Positive_regulation (positive) of EMA associated with rhinitis and cancer
15) Confidence 0.03 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2391140 Disease Relevance 0.98 Pain Relevance 0

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