INT157528

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GRM5) cytoplasm (GRM5) signal transducer activity (GRM5)
GRM5 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 99.68 Very High Very High Very High
Enkephalin 1 98.32 Very High Very High Very High
opioid receptor 11 97.56 Very High Very High Very High
Glutamate receptor 3 93.88 High High
antagonist 2 88.96 High High
tolerance 1 84.04 Quite High
analgesia 1 83.48 Quite High
Opioid 1 83.08 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As demonstrated by the D-Ala2,N-MePhe4,Gl-ol5-enkephalin (DAMGO)-induced inhibition of intracellular cAMP level and by binding studies, the co-expression of mGluR5 had no substantial effect on the agonist binding sites and functional coupling of the MOR.
Neg (no) Regulation (effect) of Gene_expression (co-expression) of mGluR5 associated with agonist, opioid receptor and enkephalin
1) Confidence 0.43 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 19162047 Disease Relevance 0 Pain Relevance 0.96

General Comments

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