INT157539

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) intracellular (SP1)
DNA binding (SP1) signal transducer activity (OPRM1) cytoplasm (SP1)
Anatomy Link Frequency
lymphocytes 6
SP1 (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
mu opioid receptor 16 100.00 Very High Very High Very High
Morphine 4 92.76 High High
addiction 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Syndrome 2 95.68 Very High Very High Very High
Immunodeficiency 6 95.32 Very High Very High Very High
Infection 10 90.16 High High
Repression 4 75.00 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 5.00 Very Low Very Low Very Low
Morphine Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous investigation has suggested that expression of the MOR gene in lymphocytes is triggered by cooperative interaction between transcription factors, specificity protein 1 (Sp1) and Ying Yang 1 (YY1), in the promoter region.
Sp1 Binding (interaction) of in lymphocytes Regulation (triggered) of Gene_expression (expression) of MOR gene in lymphocytes associated with mu opioid receptor
1) Confidence 0.36 Published 2009 Journal J. Leukoc. Biol. Section Abstract Doc Link 19164126 Disease Relevance 0.60 Pain Relevance 0.36
Previous investigation has suggested that expression of the MOR gene in lymphocytes is triggered by cooperative interaction between transcription factors, specificity protein 1 (Sp1) and Ying Yang 1 (YY1), in the promoter region.
specificity protein 1 Binding (interaction) of in lymphocytes Regulation (triggered) of Gene_expression (expression) of MOR gene in lymphocytes associated with mu opioid receptor
2) Confidence 0.36 Published 2009 Journal J. Leukoc. Biol. Section Abstract Doc Link 19164126 Disease Relevance 0.60 Pain Relevance 0.36

General Comments

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