INT157605

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Context Info
Confidence 0.80
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.55
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (COL3A1) extracellular region (COL3A1)
Anatomy Link Frequency
tendons 1
fibroblasts 1
Platelet 1
COL3A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Tendonitis 3 90.28 High High
metalloproteinase 1 79.04 Quite High
cva 7 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ehlers-danlos Syndrome 53 90.40 High High
Tendinopathy 3 90.28 High High
Injury 7 55.60 Quite High
Syndrome 23 50.00 Quite Low
Disease 9 31.32 Quite Low
Osteogenesis Imperfecta 9 22.92 Low Low
Mitral Valve Prolapse 4 6.28 Low Low
Aseptic Necrosis Of Bone 8 5.00 Very Low Very Low Very Low
Rupture 8 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The study of the secretion of collagen III by skin fibroblasts may demonstrate a quantitative or qualitative deficit with abnormal migration of the pro?
Localization (secretion) of collagen III in fibroblasts
1) Confidence 0.80 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1971255 Disease Relevance 0.32 Pain Relevance 0
Platelet concentration was positively correlated with COL1A1, ratio of COL1A1:COL3A1, and COMP, and negatively correlated with COL3A1, MMP-13, and MMP-3.
Localization (ratio) of COL3A1 in Platelet
2) Confidence 0.23 Published 2009 Journal J. Orthop. Res. Section Abstract Doc Link 19170097 Disease Relevance 0 Pain Relevance 0.11
At 21 weeks, histological analysis and immunohistochemical stains with H&E and Herovici for collagen type I and III revealed mature type I collagen with normal architecture in tendons treated with cBMSC and BMMNC, while random collagen type III organization was observed in the placebo group.
Localization (organization) of collagen type III in tendons
3) Confidence 0.04 Published 2010 Journal Stem Cells International Section Body Doc Link PMC3017936 Disease Relevance 0.23 Pain Relevance 0.18

General Comments

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