INT157609

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Parp1) nuclear envelope (Parp1) intracellular (Parp1)
DNA binding (Parp1) protein complex (Parp1) nucleolus (Parp1)
Anatomy Link Frequency
nerve 1
Parp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 6 99.84 Very High Very High Very High
ischemia 50 89.44 High High
Sciatic nerve 1 75.24 Quite High
Eae 3 74.20 Quite High
Pain 1 58.72 Quite High
Inflammation 8 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 99.84 Very High Very High Very High
Apoptosis 5 94.48 High High
Death 2 91.52 High High
Cv Unclassified Under Development 46 89.44 High High
Neuropathic Pain 3 75.88 Quite High
Injury 5 74.20 Quite High
Pain 1 58.72 Quite High
Disease 1 55.68 Quite High
Brain Hemorrhage 3 50.00 Quite Low
Stroke 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, the target of the activated caspase 3, the 89-kDa PARP fragment, is significantly less expressed in the ligated nerve of physostigmine-treated rats, reaching levels that are comparable to those in the contralateral unligated nerve.
Regulation (target) of PARP in nerve
1) Confidence 0.26 Published 2009 Journal J. Neurosci. Res. Section Abstract Doc Link 19170187 Disease Relevance 0.76 Pain Relevance 0.20
In our study, the choice of a strategy targeting PARP-1 activation was based on previous studies showing that PARP-1 is also an essential component in the regulation of inflammatory response through its function as a coactivator of NF-?
Regulation (regulation) of PARP-1 associated with inflammatory response
2) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779656 Disease Relevance 0.64 Pain Relevance 0.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox