INT157669

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.05
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CDK20) cilium (CDK20) cell division (CDK20)
cytoplasm (CDK20)
Anatomy Link Frequency
coronary artery 1
CDK20 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 94.12 High High
opiate 1 33.52 Quite Low
narcan 2 31.60 Quite Low
opioid receptor 1 25.00 Low Low
cINOD 8 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Prostatitis 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 101 99.78 Very High Very High Very High
Apoptosis 7 99.22 Very High Very High Very High
Carcinoma 4 94.64 High High
INFLAMMATION 8 94.12 High High
Cv Unclassified Under Development 7 90.24 High High
Infarction 1 79.76 Quite High
Cancer 35 75.56 Quite High
Alcohol Intoxication 1 72.00 Quite High
Toxicity 2 65.76 Quite High
Disease 10 63.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using a Langendorff preparation, we show that infarct size after coronary artery ligation and reperfusion was substantially reduced by rIPC in vivo, this stimulus up-regulating the MAPKs (mitogen-activating protein kinases) p42/p44, and inducing PKCepsilon (protein kinase Cepsilon) subcellular redistribution.
Regulation (regulating) of p42 in coronary artery
1) Confidence 0.19 Published 2009 Journal Clin. Sci. Section Abstract Doc Link 19175358 Disease Relevance 0.58 Pain Relevance 0
It has been shown that sanguinarine can cause cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin dependent kinase machinery.[65] The growth inhibitory and antiproliferative effects of sanguinarine in human carcinoma cells was irrespective of their androgen status.
Regulation (modulation) of cyclin kinase associated with carcinoma, prostate cancer and apoptosis
2) Confidence 0.00 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684344 Disease Relevance 1.48 Pain Relevance 0.08

General Comments

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