INT1577
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The dopamine-mediated inhibition of prolactin secretion occurs through the binding of D2 receptors on the membrane of lactotroph cells and involves several signal transduction systems, resulting in inhibition of prolactin gene transcription, reduction of prolactin synthesis and release. | |||||||||||||||
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Elevated levels of endogenous or therapeutic glucocorticoids are associated with clinically relevant immunosuppression [40] through several mechanisms, and at the same time reduce expression and secretion of prolactin [41,42]. | |||||||||||||||
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In conclusion NLA and enflurane induced a decrease of GH and PRL plasma levels; in both groups the anaesthetic agents, at the dosage used during anaesthesia, blocked the response of these hormones to the surgical stress likely due to a block of the hypothalamic-pituitary response. | |||||||||||||||
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Similarly, the inability of amphetamine or methylphenidate to decrease serum PRL levels in man suggests important differences between the tuberoinfundibular DA neurons in man and the rat. | |||||||||||||||
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It was noteworthy that bromocriptine (BRC) therapy started in three patients caused an abrupt decrease in PRL levels. | |||||||||||||||
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The iv administration of 10 microgram/kg clonidine, but not saline, produced a rapid and significant reduction in serum PRL levels. | |||||||||||||||
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Long-term amisulpride treatment was found to lead to a constant but slow decline in prolactin levels, that remained significantly elevated until the 12th month of treatment and then significantly decreased, but still above normal range, during the first three months after suspension (Schlosser et al 2002). | |||||||||||||||
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A recent study showed that lithium affects variably prolactin secretion, in relation to duration of the therapy: a treatment of less than six months was found to increase prolactin levels as compared to controls, while bipolar patients on long term treatments (<six months) showed a decrease in prolactin levels (Basturk et al 2001). | |||||||||||||||
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Six months olanzapine was reported effective in reducing prolactin levels from 116 ng/ml to 72 ng/ml also in a woman receiving phenothiazines. | |||||||||||||||
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This means that prolactin levels increase or decrease one month before a corresponding change in the number of active lesions is observed on MRI. | |||||||||||||||
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Nevertheless, it is possible that the duration of prolactin exposure in the current study was insufficient to increase PTHrP. | |||||||||||||||
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However, prolactin levels in the first subject reached 900.6 ? | |||||||||||||||
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Combinations of drugs to reduce serum prolactin levels or antagonize the hormones's effect on the breast may be needed to obtain results. | |||||||||||||||
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1 inhibited both IGFBP-1 and PRL production in a time-dependent manner in decidual cells from 1st trimester [26], [36] and term pregnancy [27]. | |||||||||||||||
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1 reduces the expression and secretion of PRL, IGFBP-1, and TF by human ESCs decidualized in vitro, as well as primary DSCs obtained from 1st trimester decidua. | |||||||||||||||
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1 (10 ng/ml) down-regulated the expression of transcripts encoding the decidual marker proteins prolactin (PRL), insulin-like growth factor binding protein-1 (IGFBP-1) and tissue factor (TF). | |||||||||||||||
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These data show that oxytocin is capable of inhibiting the rise in ACTH and cortisol, but not in GH and PRL induced by physical exercise. | |||||||||||||||
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1-dependent decrease in expression of PRL mRNA (Figure 4C) and the amount of PRL released (Figure 4D) remained at control levels; the amount of PRL released by cells transfected with an siRNA directed against MAPK was similar to that released by cells incubated with TGF? | |||||||||||||||
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Cross-ApEn synchrony between TSH and GH did not differ between patients and controls, but TSH and PRL synchrony was reduced in patients. | |||||||||||||||
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Mean plasma prolactin levels were also observed to decrease over the course of the open-label phases. | |||||||||||||||
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