INT157848

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.74
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (FKBP5) protein folding (FKBP5) nucleolus (FKBP5)
nucleus (FKBP5) cytoplasm (FKBP5)
Anatomy Link Frequency
hippocampus 1
frontal cortex 1
FKBP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 4 99.64 Very High Very High Very High
depression 8 96.32 Very High Very High Very High
antidepressant 2 75.00 Quite High
fluoxetine 2 52.00 Quite High
Disease Link Frequency Relevance Heat
Stress 8 100.00 Very High Very High Very High
Urological Neuroanatomy 6 99.00 Very High Very High Very High
Depression 8 96.32 Very High Very High Very High
Anxiety Disorder 2 87.20 High High
Attention Deficit Hyperactivity Disorder 2 84.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, in the present study we investigated the effect of prenatal stress on behavioral changes, blood corticosterone level, concentrations of glucocorticoid receptor (GR) and its cochaperone, FKBP51, in the hippocampus and frontal cortex in adult rats.
Spec (investigated) Regulation (effect) of FKBP51 in frontal cortex associated with stress, urological neuroanatomy and hippocampus
1) Confidence 0.34 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19195790 Disease Relevance 0.87 Pain Relevance 0.26
Therefore, in the present study we investigated the effect of prenatal stress on behavioral changes, blood corticosterone level, concentrations of glucocorticoid receptor (GR) and its cochaperone, FKBP51, in the hippocampus and frontal cortex in adult rats.
Spec (investigated) Regulation (effect) of FKBP51 in hippocampus associated with stress, urological neuroanatomy and hippocampus
2) Confidence 0.11 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19195790 Disease Relevance 0.87 Pain Relevance 0.26

General Comments

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