INT15785

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Context Info
Confidence 0.45
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (AHSP) protein folding (AHSP) cytoplasm (AHSP)
Anatomy Link Frequency
plaque 2
AHSP (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 43.52 Quite Low
Disease Link Frequency Relevance Heat
Atherosclerosis 1 82.64 Quite High
Coronary Artery Disease 4 82.04 Quite High
Myocardial Infarction 1 47.36 Quite Low
Death 1 44.08 Quite Low
Cv General 3 Under Development 1 43.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For lipid lowering drugs, the exact mechanism of action is still not clear; the results of quantitated coronary angiography (QCA) revealing a small but significant increase in luminal size in stenotic areas can be explained both by stabilization of endothelial function (increased EDRF production)--as demonstrated in animal studies--leading to a decrease in basal tone, and by a decrease in plaque volume (so far not evidenced by QCA in man).
Positive_regulation (increased) of Gene_expression (production) of EDRF in plaque
1) Confidence 0.45 Published 1991 Journal Schweiz Med Wochenschr Section Abstract Doc Link 1763301 Disease Relevance 0.32 Pain Relevance 0

General Comments

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