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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (FKBP5) protein folding (FKBP5) nucleolus (FKBP5)
nucleus (FKBP5) cytoplasm (FKBP5)
Anatomy Link Frequency
frontal cortex 2
FKBP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 4 98.76 Very High Very High Very High
fluoxetine 1 93.48 High High
Hippocampus 2 86.00 High High
antidepressant 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 3 99.68 Very High Very High Very High
Depression 4 98.76 Very High Very High Very High
Stress 4 82.44 Quite High
Attention Deficit Hyperactivity Disorder 1 77.44 Quite High
Anxiety Disorder 1 75.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that the increase in hippocampal GR level and low concentration of FKBP51 in the frontal cortex may be responsible for enhanced glucocorticoid action in depression.
Positive_regulation (increase) of Negative_regulation (concentration) of FKBP51 in frontal cortex associated with depression and urological neuroanatomy
1) Confidence 0.37 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19195790 Disease Relevance 0.87 Pain Relevance 0.34

General Comments

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