INT157858

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Context Info
Confidence 0.70
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 9
Disease Relevance 9.69
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ucp1) mitochondrion (Ucp1) transmembrane transport (Ucp1)
Anatomy Link Frequency
adipose tissue 5
fat 1
Ucp1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 50 97.04 Very High Very High Very High
agonist 32 87.92 High High
Intracerebroventricular 2 75.24 Quite High
orphanin 4 75.00 Quite High
Eae 9 57.96 Quite High
Pain 1 56.28 Quite High
opioid receptor 1 53.48 Quite High
Glutamate 12 34.92 Quite Low
anesthesia 8 21.04 Low Low
cerebral cortex 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 669 99.80 Very High Very High Very High
Impaired Glucose Tolerance 50 97.04 Very High Very High Very High
Body Weight 65 92.92 High High
Diabetes Mellitus 42 90.32 High High
Overweight 6 87.16 High High
Weight Gain 12 75.00 Quite High
Hyperlipidemia 6 74.32 Quite High
Disease 8 58.40 Quite High
Gallstones 6 58.08 Quite High
Stress 9 57.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
activates the transcription of mitochondrial uncoupling protein-1 (UCP-1) in BAT through interactions with the nuclear hormone receptors PPAR?
Transcription (transcription) of UCP-1 associated with obesity
1) Confidence 0.70 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1064854 Disease Relevance 0.31 Pain Relevance 0
activates the transcription of mitochondrial uncoupling protein-1 (UCP-1) in BAT through interactions with the nuclear hormone receptors PPAR?
Transcription (transcription) of mitochondrial uncoupling protein-1 associated with obesity
2) Confidence 0.70 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1064854 Disease Relevance 0.31 Pain Relevance 0
Thus the second aim of the present study was to investigate the effect of BOF and DAI on the mRNA expression of UCP1 and UCP2 in the BAT and WAT in high-fat diet-fed mice.


Transcription (expression) of UCP1 in fat associated with obesity
3) Confidence 0.69 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.41 Pain Relevance 0.07
N/OFQ reduced rectal temperature in pair-fed mice, in keeping with decreased UCP1 mRNA expression in brown adipose tissue.
Transcription (expression) of UCP1 in adipose tissue associated with obesity
4) Confidence 0.69 Published 2009 Journal Endocrinology Section Abstract Doc Link 19196798 Disease Relevance 0.85 Pain Relevance 0.31
In addition, the mRNA expression levels of uncoupling protein 1 (UCP1) and UCP2 mRNA in WAT and brown adipose tissue (BAT) were measured. 6-week-old KK/Ta mice were divided into four groups and fed a purified powdered basal diet (the BD group), a purified high-fat (HF) powdered diet containing suet powder at 37.5 g/100 g diet (the HF group), a high-fat diet plus 1.0% bofutsushosan (BOF) treatment (the HF + BOF group), or a high-fat diet plus 1.0% daisaikoto (DAI) treatment (the HF + DAI group) for 4 weeks.
Transcription (levels) of UCP1 in adipose tissue associated with obesity
5) Confidence 0.52 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Abstract Doc Link PMC2266052 Disease Relevance 1.38 Pain Relevance 0.05
In addition, the mRNA expression levels of uncoupling protein 1 (UCP1) and UCP2 mRNA in WAT and brown adipose tissue (BAT) were measured. 6-week-old KK/Ta mice were divided into four groups and fed a purified powdered basal diet (the BD group), a purified high-fat (HF) powdered diet containing suet powder at 37.5 g/100 g diet (the HF group), a high-fat diet plus 1.0% bofutsushosan (BOF) treatment (the HF + BOF group), or a high-fat diet plus 1.0% daisaikoto (DAI) treatment (the HF + DAI group) for 4 weeks.
Transcription (levels) of uncoupling protein 1 in adipose tissue associated with obesity
6) Confidence 0.52 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Abstract Doc Link PMC2266052 Disease Relevance 1.37 Pain Relevance 0.05
In addition, the mRNA expression levels of uncoupling protein 1 (UCP1) and UCP2 mRNA in WAT and brown adipose tissue (BAT) were measured. 6-week-old KK/Ta mice were divided into four groups and fed a purified powdered basal diet (the BD group), a purified high-fat (HF) powdered diet containing suet powder at 37.5 g/100 g diet (the HF group), a high-fat diet plus 1.0% bofutsushosan (BOF) treatment (the HF + BOF group), or a high-fat diet plus 1.0% daisaikoto (DAI) treatment (the HF + DAI group) for 4 weeks.
Transcription (expression) of UCP1 in adipose tissue associated with obesity
7) Confidence 0.52 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Abstract Doc Link PMC2266052 Disease Relevance 1.38 Pain Relevance 0.05
mRNA expression of UCP1 and UCP2 in WAT and BAT
Transcription (expression) of UCP1 associated with obesity
8) Confidence 0.52 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.32 Pain Relevance 0.03
In addition, the mRNA expression levels of uncoupling protein 1 (UCP1) and UCP2 mRNA in WAT and brown adipose tissue (BAT) were measured. 6-week-old KK/Ta mice were divided into four groups and fed a purified powdered basal diet (the BD group), a purified high-fat (HF) powdered diet containing suet powder at 37.5 g/100 g diet (the HF group), a high-fat diet plus 1.0% bofutsushosan (BOF) treatment (the HF + BOF group), or a high-fat diet plus 1.0% daisaikoto (DAI) treatment (the HF + DAI group) for 4 weeks.
Transcription (expression) of uncoupling protein 1 in adipose tissue associated with obesity
9) Confidence 0.52 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Abstract Doc Link PMC2266052 Disease Relevance 1.38 Pain Relevance 0.05

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