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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 4.58
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PNLIP) small molecule metabolic process (PNLIP) extracellular region (PNLIP)
lipid metabolic process (PNLIP)
Anatomy Link Frequency
fat 1
BxPC-3 1
PNLIP (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 6 92.92 High High
GABA receptor 1 86.80 High High
antagonist 13 85.52 High High
opioid receptor 2 85.08 High High
sSRI 5 77.20 Quite High
Pain 1 73.52 Quite High
alcohol 4 71.64 Quite High
corticosteroid 1 54.80 Quite High
noradrenaline 11 51.88 Quite High
Dopamine 10 50.96 Quite High
Disease Link Frequency Relevance Heat
Hypocalcemia 1 99.92 Very High Very High Very High
Pancreatic Cancer 21 99.68 Very High Very High Very High
Obesity 46 98.84 Very High Very High Very High
Apoptosis 34 98.60 Very High Very High Very High
Metastasis 2 95.28 Very High Very High Very High
Congenital Anomalies 2 94.80 High High
Vomiting 13 93.40 High High
Pancreatitis 38 92.96 High High
Abdominal Pain 6 92.92 High High
Injury 16 85.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PTL suppressed BxPC-3 cell migration
PTL Binding (migration) of in BxPC-3
1) Confidence 0.25 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2924280 Disease Relevance 1.52 Pain Relevance 0
PTL is associated with neonatal morbidity and mortality and represents an unmet clinical need.
PTL Binding (associated) of
2) Confidence 0.17 Published 2007 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC1892056 Disease Relevance 0.22 Pain Relevance 0.03
Canine pancreatic lipase immunoreactivity (cPLI) was intended to be measured, however, the sample got lost.
Canine pancreatic lipase immunoreactivity Binding (intended) of
3) Confidence 0.15 Published 2009 Journal J Small Anim Pract Section Abstract Doc Link 19200265 Disease Relevance 0.70 Pain Relevance 0.19
It binds to gastric and pancreatic lipase thereby inactivating them; this inhibits the hydrolysis of dietary triglycerides consequently reducing the absorption of monoglycerides and free fatty acids.
pancreatic lipase Binding (binds) of
4) Confidence 0.09 Published 2006 Journal Nutr J Section Body Doc Link PMC1560153 Disease Relevance 1.11 Pain Relevance 0.19
It does not directly act on appetite as other obesity pharmacotherapies, rather it decreases fat absorption by binding to pancreatic lipase, the principle enzyme that hydrolyses triglyceride (Table 2) (Figure 1) [26].
pancreatic lipase Binding (binding) of in fat associated with obesity
5) Confidence 0.03 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC3006492 Disease Relevance 1.03 Pain Relevance 0.23

General Comments

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