INT157921

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Context Info
Confidence 0.58
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.31
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Nsf) vesicle-mediated transport (Nsf) ATPase activity (Nsf)
plasma membrane (Nsf) cytoplasm (Nsf)
Anatomy Link Frequency
fibrocytes 1
Nsf (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 16 100.00 Very High Very High Very High
Pain 2 99.64 Very High Very High Very High
Hippocampus 10 97.48 Very High Very High Very High
Pyramidal cell 3 96.72 Very High Very High Very High
Serotonin 3 72.72 Quite High
imagery 2 58.64 Quite High
Neuronal excitability 1 42.48 Quite Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nephrogenic Fibrosing Dermopathy 14 100.00 Very High Very High Very High
Contracture 1 99.90 Very High Very High Very High
Pressure And Volume Under Development 2 94.08 High High
Fibrosis 3 91.92 High High
Renal Insufficiency 1 90.56 High High
Targeted Disruption 7 84.24 Quite High
Convulsion 53 81.40 Quite High
Pain 1 80.96 Quite High
Acid Base Imbalance 1 79.28 Quite High
Disease Attributes 1 65.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Disabling and painful contractures are prominent in NSF.
Gene_expression (prominent) of NSF associated with fibrosis, pain and contracture
1) Confidence 0.58 Published 2008 Journal Med. Pregl. Section Abstract Doc Link 19203058 Disease Relevance 1.15 Pain Relevance 0.50
In particular, the expression of NSF [27] and synapsin II [28] were enriched in the CA2-CA3 region, similar to that of Brunol4.
Gene_expression (expression) of NSF
2) Confidence 0.55 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1934399 Disease Relevance 0.32 Pain Relevance 0.20
We present immunohistochemical evidence to show that the proliferating fibrocytes of NSF express phospho-70-s6 kinase (PI-3-K), a protein downstream of PI-3-K, and the target of the drug rapamycin.
Gene_expression (express) of NSF in fibrocytes associated with fibrosis
3) Confidence 0.22 Published 2010 Journal J. Am. Acad. Dermatol. Section Abstract Doc Link 20115955 Disease Relevance 0.84 Pain Relevance 0.39

General Comments

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