INT158017

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.92
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PGF) signal transduction (PGF) extracellular region (PGF)
cell-cell signaling (PGF)
Anatomy Link Frequency
placenta 1
PGF (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 10 84.44 Quite High
Clonidine 1 73.76 Quite High
dysesthesia 1 61.44 Quite High
Paresthesia 1 60.92 Quite High
peripheral neuropathy 1 59.64 Quite High
cva 18 52.36 Quite High
vincristine 2 30.76 Quite Low
dexamethasone 18 30.24 Quite Low
nud 2 27.44 Quite Low
headache 3 26.76 Quite Low
Disease Link Frequency Relevance Heat
Eclampsia 5 99.36 Very High Very High Very High
Ovarian Cancer 51 95.20 Very High Very High Very High
Fibromyalgia 5 95.04 Very High Very High Very High
Pressure And Volume Under Development 3 93.12 High High
Pre-eclampsia 136 85.84 High High
Toxicity 12 84.68 Quite High
Solid Tumor 9 83.32 Quite High
Hypertension 45 75.00 Quite High
Cancer 71 69.20 Quite High
Proteinuria 18 68.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Soluble Flt-1 binds to circulating free vascular endothelial growth factor and placenta growth factor and this is associated with endothelial dysfunction.
placenta growth factor Binding (binds) of in placenta
1) Confidence 0.18 Published 2009 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 19215236 Disease Relevance 0.34 Pain Relevance 0.07
Serum samples were assayed concurrently for sFlt1, sEng and PlGF using commercially available immunoassay kits purchased from R&D Systems (Minneapolis, MN).
PlGF Binding (sEng) of
2) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2952583 Disease Relevance 0.58 Pain Relevance 0.04
Aflibercept has a high affinity for VEGF-A, VEGF-B and placental growth factor.
placental growth factor Binding (affinity) of
3) Confidence 0.07 Published 2010 Journal OncoTargets and therapy Section Body Doc Link PMC2895781 Disease Relevance 0.78 Pain Relevance 0.15
This protein binds to VEGF-A and placental growth factor.
placental growth factor Binding (binds) of
4) Confidence 0.05 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2814233 Disease Relevance 1.21 Pain Relevance 0

General Comments

This test has worked.

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