INT158018

Context Info Confidence 0.04 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.09

extracellular region (LTBP1) proteinaceous extracellular matrix (LTBP1)

LTBP1 (Homo sapiens)

Pain Link Frequency Relevance Heat Clonidine 1 92.08

Disease Link Frequency Relevance Heat Eclampsia 5 87.88 Fibromyalgia 2 83.56 Hypertension 1 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Soluble endoglin, a transforming growth factor (TGF)-beta coreceptor, was reported to synergize with sFlt-1 to amplify endothelial dysfunction by inhibiting TGF-beta1-mediated vasorelaxation. 2.

Negative_regulation (inhibiting) of TGF-beta1-mediated

1) Confidence 0.04 Published 2009 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 19215236 Disease Relevance 0.39 Pain Relevance 0.09

General Comments

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