INT158084

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.82
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FGD1) signal transduction (FGD1) Golgi apparatus (FGD1)
plasma membrane (FGD1) cytoskeleton (FGD1) nucleus (FGD1)
Anatomy Link Frequency
plasma 1
FGD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 99.34 Very High Very High Very High
Angina 27 98.80 Very High Very High Very High
cva 31 92.88 High High
Pain 5 82.36 Quite High
anesthesia 17 54.00 Quite High
allodynia 2 50.00 Quite Low
Migraine 1 50.00 Quite Low
agonist 1 42.72 Quite Low
Enkephalin 3 24.60 Low Low
substance P 3 23.96 Low Low
Disease Link Frequency Relevance Heat
Syndrome 21 100.00 Very High Very High Very High
Angina 30 98.80 Very High Very High Very High
Acute Coronary Syndrome 24 93.28 High High
Pulmonary Embolism 25 92.88 High High
Neuropathic Pain 2 80.56 Quite High
Emergencies 2 71.44 Quite High
Malaria 11 50.00 Quite Low
Pain 2 50.00 Quite Low
Headache 1 50.00 Quite Low
INFLAMMATION 16 21.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: Analyses were performed with data collected prospectively from patients in 2 recently completed early intervention trials, AXERT Early miGraine Intervention Study (AEGIS) and AXERT 12.5 mg time vs Intensity Migraine Study (AIMS): 2-hour pain free, 2-hour pain relief (AEGIS only), sustained pain free (SPF), use of rescue medication, and median headache duration (AIMS only), in the presence and absence of pretreatment AAS, which was determined by responses to a questionnaire.
Negative_regulation (absence) of AAS
1) Confidence 0.21 Published 2009 Journal Headache Section Body Doc Link 19220503 Disease Relevance 0.08 Pain Relevance 0
The two groups were well managed even though a vast literature recommends that a FGD be limited to at-most 12 participants.
Negative_regulation (limited) of FGD
2) Confidence 0.08 Published 2010 Journal Malar J Section Body Doc Link PMC2837674 Disease Relevance 0 Pain Relevance 0
The diagnostic delay of AAS is also a serious problem worldwide.
Negative_regulation (delay) of AAS associated with syndrome
3) Confidence 0.03 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC3008823 Disease Relevance 1.74 Pain Relevance 0.59
In addition, for four AAS plasma, which led to a 37.3 ± 10.4% decrease of HLA-DR expression onto CD14HIGHmonocytes from healthy controls, the co-incubation with RU486, a glucocorticoid receptor antagonist, fully abolished the inhibitory effect of the active AAS plasma (data not shown).


Negative_regulation (effect) of AAS in plasma associated with antagonist
4) Confidence 0.01 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0 Pain Relevance 0.10

General Comments

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