INT158183

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ARRB2) cytoplasmic membrane-bounded vesicle (ARRB2) plasma membrane (ARRB2)
nucleus (ARRB2) cytoplasm (ARRB2)
ARRB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 9 100.00 Very High Very High Very High
Opioid 5 78.32 Quite High
Pain 2 77.44 Quite High
opioid receptor 1 62.72 Quite High
Disease Link Frequency Relevance Heat
Death 8 98.48 Very High Very High Very High
Apoptosis 2 88.80 High High
Breast Cancer 3 84.76 Quite High
Pain 2 77.44 Quite High
Cancer 2 73.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, blockade of morphine-induced cell death by beta-arrestin2 seems to be dependent on the inhibition of caspase-8, as inhibition of beta-arrestin2 and morphine treatment significantly enhanced the levels of cleaved caspase-8.
Positive_regulation (enhanced) of Negative_regulation (inhibition) of beta-arrestin2 associated with death and morphine
1) Confidence 0.35 Published 2009 Journal Neoplasma Section Abstract Doc Link 19239323 Disease Relevance 1.13 Pain Relevance 1.33

General Comments

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