INT158245

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CCR2) plasma membrane (CCR2) cytoplasm (CCR2)
signal transducer activity (CCR2)
CCR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 1 83.56 Quite High
abdominal pain 1 66.72 Quite High
headache 1 66.08 Quite High
Disease Link Frequency Relevance Heat
Vomiting 1 67.12 Quite High
Abdominal Pain 1 66.72 Quite High
Headache 1 66.08 Quite High
Atherosclerosis 2 59.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings indicate that the inhibitory effects of evodiamine and rutaecarpine on LIGHT-induced migration and the activation of CCR1, CCR2, ICAM-1, ERK, and p38 MAPK occurs via decreased ROS production and NADPH oxidase activation.
Negative_regulation (decreased) of Positive_regulation (activation) of CCR2
1) Confidence 0.37 Published 2009 Journal J. Cell. Biochem. Section Abstract Doc Link 19241441 Disease Relevance 0.26 Pain Relevance 0.17

General Comments

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