INT158313

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.96
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Psd) intracellular (Psd) cytoplasm (Psd)
Anatomy Link Frequency
middle cerebral artery 1
Psd (Mus musculus)
Pain Link Frequency Relevance Heat
depression 8 100.00 Very High Very High Very High
Inflammation 6 85.20 High High
Analgesic 2 84.28 Quite High
fluoxetine 1 81.36 Quite High
psoriasis 1 66.48 Quite High
adenocard 2 36.64 Quite Low
Pyramidal cell 6 25.20 Quite Low
Hippocampus 9 25.00 Low Low
antidepressant 1 25.00 Low Low
withdrawal 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 8 100.00 Very High Very High Very High
Middle Cerebral Artery Infarction 1 99.84 Very High Very High Very High
Cancer 3 99.34 Very High Very High Very High
Injury 10 97.92 Very High Very High Very High
Stress 4 95.00 High High
Creutzfeldt Jakob Disease 12 93.68 High High
Wallerian Degeneration 15 87.40 High High
INFLAMMATION 6 85.20 High High
Targeted Disruption 2 70.28 Quite High
Ulcers 1 68.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A mouse model of PSD was induced by middle cerebral artery occlusion (MACO) 30 min/reperfusion, followed by isolation feeding and chronic unpredictable mild stress for 2 weeks.
Positive_regulation (induced) of PSD in middle cerebral artery associated with stress, depression and middle cerebral artery infarction
1) Confidence 0.39 Published 2009 Journal Anatomical record (Hoboken, N.J. : 2007) Section Abstract Doc Link 19248161 Disease Relevance 0.74 Pain Relevance 0.27
Perhaps the most striking feature of the prion-induced synaptic pathology is the increased curvature of the PSD.
Positive_regulation (increased) of PSD
2) Confidence 0.25 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2954441 Disease Relevance 0.51 Pain Relevance 0
Among them, glucosyldiacylglycerol has been reported to have a few biological effects, including significant fibrinolysis [13, 14], specific inhibition of tumor [15], and increased the cloning activation of phosphatidylserine decarboxylase in both the Bacillus subtilis null pss and psd mutants [16].
Positive_regulation (activation) of psd associated with cancer
3) Confidence 0.06 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2707035 Disease Relevance 0.71 Pain Relevance 0.16

General Comments

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