INT158354

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.21
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
Anatomy Link Frequency
paw 2
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory marker 10 99.40 Very High Very High Very High
Inflammation 46 96.60 Very High Very High Very High
Pain 1 86.60 High High
Arthritis 1 76.04 Quite High
cINOD 2 60.96 Quite High
Analgesic 3 25.00 Low Low
COX2 2 25.00 Low Low
cOX1 1 25.00 Low Low
alcohol 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 58 99.08 Very High Very High Very High
Nicotine Addiction 6 95.76 Very High Very High Very High
Obesity 6 95.28 Very High Very High Very High
Nociception 4 91.24 High High
Aging 1 88.68 High High
Pain 1 86.60 High High
Cytomegalovirus Infection 11 85.52 High High
Arthritis 1 76.04 Quite High
Coronary Artery Disease 1 74.60 Quite High
Atherosclerotic Plaque 1 62.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, associations with IL-6 persisted after adjustment for age, race and socioeconomic factors but were reduced and no longer statistically significant after adjustment for potential mediators of inflammation such as smoking and obesity.
Negative_regulation (reduced) of IL-6 Binding (associations) of associated with nicotine addiction, inflammation and obesity
1) Confidence 0.20 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2996373 Disease Relevance 1.26 Pain Relevance 0.29
The administration of alphaLA 1 h before carrageenan injection inhibited the increased formation of IL-6 and PGE(2) in paw exudates.
Negative_regulation (inhibited) of IL-6 Binding (formation) of in paw
2) Confidence 0.12 Published 2009 Journal Biol. Pharm. Bull. Section Abstract Doc Link 19252279 Disease Relevance 0.95 Pain Relevance 0.42

General Comments

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