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Context Info
Confidence 0.38
First Reported 1991
Last Reported 1991
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.34

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signal transduction (CGA) small molecule metabolic process (CGA) extracellular region (CGA)
cellular nitrogen compound metabolic process (CGA) cell-cell signaling (CGA)
Anatomy Link Frequency
midbrain 2
CGA (Homo sapiens)
Pain Link Frequency Relevance Heat
midbrain 2 100.00 Very High Very High Very High
Opioid 3 99.98 Very High Very High Very High
Disease Link Frequency Relevance Heat
Tics 1 98.76 Very High Very High Very High
Syndrome 5 97.76 Very High Very High Very High
Encephalitis 1 86.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the following communication we discuss evidence suggesting that an abnormal opioid-gonadotrophin interaction at the midbrain may be essential to the clinical expression of vocal tics in Tourette's Syndrome (TS).
Spec (may) Positive_regulation (essential) of gonadotrophin Binding (interaction) of in midbrain associated with tics, syndrome, midbrain and opioid
1) Confidence 0.38 Published 1991 Journal Med. Hypotheses Section Abstract Doc Link 1766421 Disease Relevance 0.54 Pain Relevance 0.34

General Comments

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