INT158402

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.96
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Coq10a) cellular_component (Coq10a) biological_process (Coq10a)
Anatomy Link Frequency
brains 2
Coq10a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 96.80 Very High Very High Very High
cytokine 2 95.76 Very High Very High Very High
induced neuropathy 2 50.00 Quite Low
cerebral cortex 2 42.48 Quite Low
Hippocampus 2 8.56 Low Low
Pain 2 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
peripheral neuropathy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 98.40 Very High Very High Very High
INFLAMMATION 2 96.80 Very High Very High Very High
Cancer 2 91.68 High High
Neuropathic Pain 2 91.48 High High
Necrosis 2 91.12 High High
Amyloid Plaque 6 65.20 Quite High
Alzheimer's Dementia 8 56.88 Quite High
Disease 8 49.28 Quite Low
Neurodegenerative Disease 16 46.80 Quite Low
Cognitive Disorder 2 36.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Certain gangliosides, including GM1, have also been reported to inhibit A?
Regulation (reported) of Gene_expression (gangliosides) of GM1
1) Confidence 0.37 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2838405 Disease Relevance 0.41 Pain Relevance 0.10
In AD brains, GM1 ganglioside, one of the major brain gangliosides, is considered to bind to monomeric A?
Regulation (one) of Gene_expression (ganglioside) of GM1 in brains
2) Confidence 0.37 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2838405 Disease Relevance 0.46 Pain Relevance 0.06
MATERIAL AND METHOD: Fifty-four Wistar rats were divided into control, vehicle for paclitaxel (Cremophor EL), paclitaxel, and paclitaxel + GM1 groups.
Regulation (control) of Gene_expression (groups) of GM1
3) Confidence 0.35 Published 2009 Journal J Med Assoc Thai Section Body Doc Link 19260244 Disease Relevance 0.09 Pain Relevance 0

General Comments

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