INT158436

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2009
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.15
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Abcc2)
Anatomy Link Frequency
liver 2
placenta 1
Abcc2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 15 99.24 Very High Very High Very High
isoflurane 3 95.76 Very High Very High Very High
Morphine 6 50.00 Quite Low
Bile 20 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 4 92.56 High High
Toxicity 4 5.00 Very Low Very Low Very Low
Stress Incontinence 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in the expression of multidrug resistance-associated proteins (MRP2 and MRP3) and UDP-glucuronosyltransferase 2B1 (UGT2B1) mRNA in the liver were also estimated by reverse-transcriptase PCR.
Transcription (expression) of MRP2 in liver
1) Confidence 0.47 Published 2010 Journal J. Pharm. Pharmacol. Section Body Doc Link 20487213 Disease Relevance 0.09 Pain Relevance 0
The expression of MRP3 and UGT2B1 mRNA was increased in STZ-diabetic rats, whereas expression of MRP2 mRNA was decreased.
Transcription (expression) of MRP2
2) Confidence 0.47 Published 2010 Journal J. Pharm. Pharmacol. Section Body Doc Link 20487213 Disease Relevance 0.06 Pain Relevance 0
Quantitative expression of Mrp1, Mrp2, and Oatp4a1 mRNA in maternal liver and placenta was investigated by real-time RT-PCR using the QuantiTect SYBR Green PCR kit (Qiagen) and analyzed by iQ5/MyiQ Single-Color (Bio-Rad Laboratories Inc., Hercules, CA, USA).
Spec (investigated) Transcription (expression) of Mrp2 in placenta
3) Confidence 0.43 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2944077 Disease Relevance 0 Pain Relevance 0
The mRNA expression ratios of eight genes encoding DMEs that showed the greatest alterations in the previous study, namely Cyp7a1, Cyp2b15, Por, Nr1i2, Ces2, Ugt1a7, Abcb1a and Abcc2, were measured by quantitative real-time reverse transcriptase-polymerase chain reaction.
Transcription (expression) of Abcc2
4) Confidence 0.20 Published 2009 Journal Biomed. Res. Section Abstract Doc Link 19265259 Disease Relevance 0 Pain Relevance 0.94
Quantitative expression of Mrp1, Mrp2, and Oatp4a1 mRNA in maternal liver and placenta was investigated by real-time RT-PCR using the QuantiTect SYBR Green PCR kit (Qiagen) and analyzed by iQ5/MyiQ Single-Color (Bio-Rad Laboratories Inc., Hercules, CA, USA).
Spec (investigated) Transcription (expression) of Mrp2 in liver
5) Confidence 0.15 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2944077 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox