INT158453

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (TRAM1) translation (TRAM1)
TRAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 8 100.00 Very High Very High Very High
Opioid 1 99.60 Very High Very High Very High
monoamine 1 99.12 Very High Very High Very High
Antinociceptive 1 99.04 Very High Very High Very High
Serotonin 1 96.88 Very High Very High Very High
antinociception 2 91.12 High High
tail-flick 1 86.80 High High
analgesia 1 75.00 Quite High
Potency 1 46.56 Quite Low
Pain 2 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of the present study was to evaluate the nature of the antinociceptive interaction among dexketoprofen (DEX), a mixed inhibitor of the cyclo-oxygenases, and tramadol (TRAM), a weak opioid with monoaminergic activity that inhibits norepinephrine and serotonin re-uptake.
Negative_regulation (inhibitor) of TRAM associated with tramadol, serotonin, opioid, antinociceptive and monoamine
1) Confidence 0.36 Published 2009 Journal Fundam Clin Pharmacol Section Abstract Doc Link 19267773 Disease Relevance 0 Pain Relevance 0.92

General Comments

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