INT158508

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.74
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (STAT3) DNA binding (STAT3) cytoplasm (STAT3)
signal transducer activity (STAT3) cell proliferation (STAT3) cytosol (STAT3)
Anatomy Link Frequency
HSG 2
STAT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 91.88 High High
Inflammation 48 56.40 Quite High
agonist 86 50.00 Quite Low
cINOD 4 50.00 Quite Low
ischemia 8 5.00 Very Low Very Low Very Low
dexamethasone 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 297 99.08 Very High Very High Very High
Acute-phase Reaction 2 93.28 High High
INFLAMMATION 55 91.52 High High
Skin Cancer 3 83.24 Quite High
Hypoxia 10 79.00 Quite High
Hematologic Neoplasms 78 50.00 Quite Low
Malignant Neoplastic Disease 22 50.00 Quite Low
Malignant Tumors Of Salivary Glands 1 50.00 Quite Low
Apoptosis 54 47.92 Quite Low
Precancerous Conditions 2 20.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Messenger RNA and protein expression of Stat3 and survivin was detected in HSY and HSG cell lines.
Negative_regulation (detected) of Gene_expression (expression) of Stat3 in HSG
1) Confidence 0.43 Published 2009 Journal Oral Surg Oral Med Oral Pathol Oral Radiol Endod Section Body Doc Link 19272804 Disease Relevance 0.16 Pain Relevance 0
Inhibition of Stat3 activation blocks HIF-1 and VEGF expression in vitro and inhibits tumor growth and angiogenesis in vivo [151].
Negative_regulation (Inhibition) of Gene_expression (expression) of Stat3 associated with cancer
2) Confidence 0.24 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.79 Pain Relevance 0.07
Inhibition of Stat3 activation blocks HIF-1 and VEGF expression in vitro and inhibits tumor growth and angiogenesis in vivo [151].
Negative_regulation (blocks) of Gene_expression (expression) of Stat3 associated with cancer
3) Confidence 0.24 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.79 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox