INT158582

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Context Info
Confidence 0.41
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP1A2) oxidoreductase activity (CYP1A2) endoplasmic reticulum (CYP1A2)
enzyme binding (CYP1A2)
CYP1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 10.00 Low Low
Disease Link Frequency Relevance Heat
Myalgia 2 50.00 Quite Low
Emergencies 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A pharmacokinetic interaction between ciprofloxacin and the patient's comedication carbamazepine is unlikely to be the responsible mechanism, since fluoroquinolones inhibit cytochrome P450 isoenzyme CYP1A2 but not CYP3A4 which metabolizes carbamazepine.
Negative_regulation (inhibit) of Positive_regulation (cytochrome) of CYP1A2
1) Confidence 0.41 Published 2009 Journal Int J Clin Pharmacol Ther Section Body Doc Link 19281725 Disease Relevance 0 Pain Relevance 0

General Comments

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