INT158592

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Context Info
Confidence 0.19
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CSK) Golgi apparatus (CSK) plasma membrane (CSK)
cytoplasm (CSK)
CSK (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 95.16 Very High Very High Very High
Inflammation 3 83.84 Quite High
metalloproteinase 1 78.76 Quite High
Paracetamol 1 60.32 Quite High
diclofenac 1 58.88 Quite High
Inflammatory response 1 53.96 Quite High
qutenza 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Adhesions 2 99.48 Very High Very High Very High
Chronic Myeloid Leukemia 1 99.26 Very High Very High Very High
Dermatitis 1 75.00 Quite High
INFLAMMATION 2 53.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dasatinib was approved in 2006 for the treatment of imatinib-resistant chronic myelogenous leukemia and functions primarily through the inhibition of BCR-ABL and Src kinase.
Negative_regulation (inhibition) of Src kinase associated with chronic myeloid leukemia
1) Confidence 0.19 Published 2009 Journal Drug Metab. Dispos. Section Abstract Doc Link 19282395 Disease Relevance 0.10 Pain Relevance 0.09
Inhibition of Src kinase activity and ROS may inhibit the EGFR activation.
Negative_regulation (Inhibition) of Src kinase
2) Confidence 0.04 Published 2010 Journal Free Radic. Biol. Med. Section Abstract Doc Link 20123015 Disease Relevance 0.33 Pain Relevance 0.27

General Comments

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